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Identification and validation of a novel mature microRNA encoded by the Merkel cell polyomavirus in human Merkel cell carcinomas.
BACKGROUND Merkel cell polyomavirus (MCPyV) is present in approximately 80% of human Merkel cell carcinomas (MCCs). A previous in silico prediction suggested MCPyV encodes a microRNA (miRNA) that mayExpand
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Merkel Cell Polyomavirus Large T Antigen Has Growth-Promoting and Inhibitory Activities
ABSTRACT Merkel cell carcinoma (MCC) is a rare and aggressive form of skin cancer. In at least 80% of all MCC, Merkel cell polyomavirus (MCPyV) DNA has undergone clonal integration into the host cellExpand
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Merkel cell polyomavirus is not detected in prostate cancers, surrounding stroma, or benign prostate controls.
BACKGROUND Merkel cell polyomavirus (MCV or MCPyV) is a recently discovered human polyomavirus that is implicated in the pathogenesis of Merkel cell carcinoma (MCC). Although the transmission routeExpand
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Reversal of epigenetic silencing of MHC class I chain-related protein A and B improves immune recognition of Merkel cell carcinoma
Merkel cell carcinoma (MCC) is a virally associated cancer characterized by its aggressive behavior and strong immunogenicity. Both viral infection and malignant transformation induce expression ofExpand
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Augmentation of adoptive T-cell therapy for Merkel cell carcinoma with avelumab.
3044Background: 80% of Merkel cell carcinomas (MCCs) are caused by Merkel cell polyomavirus (MCPyV) oncoproteins. Although absent in most cases, abundant MCPyV-specific CD8+ TIL are associated withExpand
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Diagnostic Biopsy Does Not Commonly Induce Intratumoral CD8 T Cell Infiltration in Merkel Cell Carcinoma
Background Merkel cell carcinoma is a polyomavirus-associated cancer that is strongly linked with T lymphocyte immune suppression in epidemiologic studies. CD8+ T cell infiltration into MCC tumorsExpand
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Relevance of rank for a mixed state quantum teleportation resource
Mixed entangled states are generic resource for quantum teleportation. Optimal teleportation fidelity measures the success of quantum teleportation. The relevance of rank in the teleportation processExpand
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Bounds on mixedness and entanglement of quantum teleportation resources
Abstract For a standard teleportation protocol, rank dependent upper bounds on Von Neumann entropy and linear entropy beyond which the states of respective ranks cease to be useful for quantumExpand
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