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Establishment and Characterization of a Human Cell Line Derived from a Squamous Cell Carcinoma of the Tongue
Application of coomassie brilliant blue staining to cultured hepatocytes.
Coomassie brilliant blue staining developed by Pena (1980) was applied to cultured hepatocytes of adult rats with some modifications. Many of organelles in the cytoplasms were clearly visible as blue… Expand
Effects of various concentrations of ethyl-alpha-p-chlorophenoxyisobutyrate (clofibrate) on diethylnitrosamine-induced hepatic tumorigenesis in the rat.
Male F344 rats were given diethylnitrosamine in drinking water at a concentration of 40 p.p.m. for 5 weeks. One week later, the rats were fed diet containing clofibrate at concentrations of of 0,0.1,… Expand
Changes in peroxisomes in preneoplastic liver and hepatoma of mice induced by alpha-benzene hexachloride.
Peroxisomes in hepatomas and hyperplastic preneoplastic liver lesions induced in mice by 500 ppm alpha-benzene hexachloride were examined histochemically and electron microscopically. Although most… Expand
Estimation of resistance to dimethylnitrosamine of normal hepatocytes, hyperplastic nodule cells and hepatoma cells of rats in primary culture.
Normal hepatocytes, hyperplastic nodule cells and hepatoma cells of rats induced by 2-acetylaminofluorene treatment were transferred to primary culture. After exposure of the cells to… Expand
Polygonal networks, "geodomes", of adult rat hepatocytes in primary culture.
- Y. Mochizuki, K. Furukawa, T. Mitaka, T. Yokoi, T. Kodama
- Biology, Medicine
- Cell biology international reports
Polygonal networks, "geodomes", in cultured hepatocytes of adult rats were examined by both light and electron microscopy. On light microscopical examinations of specimens stained with Coomassie blue… Expand
In vitro measurement of resistance to phalloidin and gamma-glutamyltransferase of carcinogen-induced preneoplastic hepatocytes of rats.
- N. Sawada, K. Furukawa, H. Tsukada
- Biology, Medicine
- Journal of the National Cancer Institute
- 1 September 1982
Male inbred F344 rats weighing about 150 g were fed continuously a diet containing 0.02% N-2-fluorenylacetamide for 14-15 weeks. The presumptively preneoplastic hepatocytes were transferred to an in… Expand
HISTOCHEMICAL INVESTIGATION OF HEPATIC GAMMA-GLUTAMYL-TRANSPEPTIDASE OF RATS TREATED WITH HIGH DOSE OF PHENOBARBITAL
Hepatic gamma-glutamyl transpeptidase (GGTP) induced by the administration of 0.2% phenobarbital (PB) for 20 weeks in rats was investigated histochemically. By the PB treatment, centrolobular and… Expand
A Highly Efficient Method for Obtaining Clonal Epithelial Cells Proliferating in Cultures from Adult Rat Liver : Development of Epithelial Cell Colonies in Cultures of Cells Derived from…
Dose-dependent enhancing effect of phenobarbital on hepatocarcinogenesis initiated by diethylnitrosamine in the rat.
Sequential feeding of various dose levels of phenobarbital (PB) after diethylnitrosamine (DENA) administration revealed that the enhancing effect of PB on hepatocarcinogenesis was dose-dependent. The… Expand