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- Publications
- Influence
Antitumor activity of amino acid derivatives in the primary screening.
- K. Fukushima, S. Toyoshima
- Biology, Medicine
- Gan
- 28 February 1975
Approximately 350 amino acid derivatives were synthesized and tested for antitumor activity in four tumor systems. The effect on life prolongation and tumor growth was examined using mouse leukemia… Expand
Special articles on new aspects of silicon chemistry. Biological activity of organo silicon compounds. Study on cancer chemotherapeutic activity.
- H. Fujita, K. Fukushima, +7 authors Toshinobu Ishihara
- Chemistry
- 1990
有… Expand
Toxicologic studies of antitumor amino acid derivatives in mice and rats.
- K. Fukushima, Sogen Itoh, S. Toyoshima
- Medicine
- 1974
Toxicity of five antitumor amino acid derivatives, N-β-naphthalenesulfonyl-DL-tryptophan(A-91), β-naphthylaminomethyl-γ-aminobutyric acid (A-144), N-ethylcarbaminomethyl-L-isoleucine(A-145),… Expand
Phenylalanine derivatives and their use for promoting drug absorption
- S. Toyoshima, S. Toyoshima, +5 authors I. Kumashiro
- Chemistry
- 28 April 1983
Antitumor Activity of Vinyl Polymer Immobilized 5-Fluorouracils through Organosilicon-Amine Spacer Groups via Urea Bonds
- Y. Ohya, T. Nakao, T. Ouchi, Takeshi Inoi, K. Fukushima, T. Tashiro
- Materials Science
- 1 July 1992
Abstract The homopolymerization of vinyl monomer immobilized 5-fluorouracils (5FU) through organosilicon-amine spacer groups via urea bonds (KY-20) and the copolymerization of KY-20 with vinyl… Expand
Studies on the anti-diabetic activity of amino acid derivatives.(1)
- Yoshiko Seto, M. Fukuma, K. Fukushima, S. Toyoshima
- Chemistry
- 1981
antitumor agent and antimetastatic agent containing an inhibitor of ribonuclease as the active component
- K. Fukushima, T. Honjo, T. Fujita, H. Fujita, T. Sakurai
- Chemistry
- 30 October 1989
The invention relates to an antitumor agent and an antimetastatic agent containing a ribonuclease inhibitor as the active component.
AN ALTERNATIVE ROUTE TO PERALKYLCYCLOPOLYSILANES: THE REACTION OF 1,2-DICHLOROTETRAALKYLDISILANES WITH LITHIUM
- H. Watanabe, J. Inose, K. Fukushima, Y. Kougo, Y. Nagai
- Chemistry
- 5 November 1983
The reaction of 1,2-dichlorotetraalkyldisilanes, Cl(R1R2Si)2Cl (R1=R2=iPr; R1, R2=iPr, Me; R1, R2=Me3SiCH2, Me; R1, R2=tBuCH2, Me; R1, R2=tBu, Me), with an excess amount of lithium in tetrahydrofuran… Expand