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Antitumor activity of amino acid derivatives in the primary screening.
Approximately 350 amino acid derivatives were synthesized and tested for antitumor activity in four tumor systems. The effect on life prolongation and tumor growth was examined using mouse leukemiaExpand
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Toxicologic studies of antitumor amino acid derivatives in mice and rats.
Toxicity of five antitumor amino acid derivatives, N-β-naphthalenesulfonyl-DL-tryptophan(A-91), β-naphthylaminomethyl-γ-aminobutyric acid (A-144), N-ethylcarbaminomethyl-L-isoleucine(A-145),Expand
Antitumor Activity of Vinyl Polymer Immobilized 5-Fluorouracils through Organosilicon-Amine Spacer Groups via Urea Bonds
Abstract The homopolymerization of vinyl monomer immobilized 5-fluorouracils (5FU) through organosilicon-amine spacer groups via urea bonds (KY-20) and the copolymerization of KY-20 with vinylExpand
antitumor agent and antimetastatic agent containing an inhibitor of ribonuclease as the active component
The invention relates to an antitumor agent and an antimetastatic agent containing a ribonuclease inhibitor as the active component.
AN ALTERNATIVE ROUTE TO PERALKYLCYCLOPOLYSILANES: THE REACTION OF 1,2-DICHLOROTETRAALKYLDISILANES WITH LITHIUM
The reaction of 1,2-dichlorotetraalkyldisilanes, Cl(R1R2Si)2Cl (R1=R2=iPr; R1, R2=iPr, Me; R1, R2=Me3SiCH2, Me; R1, R2=tBuCH2, Me; R1, R2=tBu, Me), with an excess amount of lithium in tetrahydrofuranExpand
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