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Solubilization of fullerenes into water with polyvinylpyrrolidone applicable to biological tests
C60 and C70 can be solubilized into water with poly(vinylpyrrolidone)(PVP) and the aqueous solutions of C60 and C70 are applied to haemolysis test.
Resveratrol as a new type of DNA-cleaving agent.
Evidence is provided that resveratrol is capable of binding to DNA, and that the Cu(2+)-dependent DNA damage is more likely caused by a copper-peroxide complex rather than by a freely diffusible oxygen species. Expand
Photoinduced nitric oxide release from a hindered nitrobenzene derivative by two-photon excitation.
This is the first account of a non-nitrosyl-chelated metal ion containing NO donor which can be controlled by the TPE technique. Expand
Conversion of procyanidin B-type (catechin dimer) to A-type: evidence for abstraction of C-2 hydrogen in catechin during radical oxidation
Abstract Procyanidin B-1 and B-2 were converted into A-1 and A-2 by radical oxidation using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals under neutral conditions, respectively. Transformation ofExpand
Resveratrol, a naturally occurring polyphenol, induces sister chromatid exchanges in a Chinese hamster lung (CHL) cell line.
The results suggest that resveratrol may preferentially induce SCE but not CA, that is, it may cause S phase arrest only when SCEs are induced. Expand
Efficient radical scavenging ability of artepillin C, a major component of Brazilian propolis, and the mechanism.
Hydrogen transfer from artepillin C to cumylperoxyl radical proceeds via one-step hydrogen atom transfer rather than via electron transfer, the rate constant of which is comparable to that ofExpand
Activation of the human Ah receptor by aza-polycyclic aromatic hydrocarbons and their halogenated derivatives.
Results suggest that even monohalogenation markedly enhances AhR ligand activity in aza-PAHs, which is similar or more potent than the corresponding parent PAHs. Expand
The 4'-hydroxy group is responsible for the in vitro cytogenetic activity of resveratrol.
Results suggested that a 4'-hydroxy group is essential to the genotoxicity of stilbenes. Expand
Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy.
Three estrogen receptor degradation inducers are designed and synthesized, which crosslink the ER and the cellular inhibitor of apoptosis protein 1 (cIAP1) resulting in its proteasomal degradation. Expand
Structural basis for DNA-cleaving activity of resveratrol in the presence of Cu(II).
The results show that the 4-hydroxystilbene structure of 1 is a major determinant of generation of reactive oxygen species that was responsible for DNA strand scission. Expand