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Enantioselective indole Friedel--Crafts alkylations catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes.
- D. A. Evans, K. Scheidt, K. Fandrick, H. W. Lam, Jimmy Wu
- Chemistry, Medicine
- Journal of the American Chemical Society
- 11 December 2007
A highly enantioselective Friedel-Crafts alkylation of electron-rich aromatic nucleophiles catalyzed by scandium(III) triflate-pyridyl(bis)oxazoline complexes has been accomplished. The reaction… Expand
Enantioselective Friedel-Crafts alkylations catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes.
- D. A. Evans, K. Fandrick, Hyun-Ji Song, K. Scheidt, R. Xu
- Chemistry, Medicine
- Journal of the American Chemical Society
- 13 August 2003
The enantioselective Friedel-Crafts addition of a variety of indoles catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes (Sc(III)-pybox) was accomplished utilizing a series of… Expand
Enantioselective Nitrone Cycloadditions of α,β-Unsaturated 2-Acyl Imidazoles Catalyzed by Bis(oxazolinyl)pyridine—Cerium(IV) Triflate Complexes.
- D. A. Evans, Hyun-Ji Song, K. Fandrick
- Chemistry
- 14 November 2006
Enantioselective Friedel−Crafts Alkylations of α,β-Unsaturated 2-Acyl Imidazoles Catalyzed by Bis(oxazolinyl)pyridine−Scandium(III) Triflate Complexes
- D. A. Evans, K. Fandrick, Hyun-Ji Song
- Chemistry
- 4 June 2005
An enantioselective Friedel−Crafts alkylation with α,β-unsaturated 2-acyl imidazoles and electron-rich aromatic nucleophiles catalyzed by bis(oxazolinyl)pyridine−scandium(III) triflate complexes has… Expand
Copper catalyzed asymmetric propargylation of aldehydes.
- Daniel R Fandrick, K. Fandrick, +8 authors C. Senanayake
- Chemistry, Medicine
- Journal of the American Chemical Society
- 18 May 2010
The highly enantio- and regioselective copper catalyzed asymmetric propargylation of aldehydes with a propargyl borolane reagent is reported. The methodology demonstrated broad functional group… Expand
Enantioselective Nitrone Cycloadditions of α,β-Unsaturated 2-Acyl Imidazoles Catalyzed by Bis(oxazolinyl)pyridine−Cerium(IV) Triflate Complexes
- D. A. Evans, Hyun-Ji Song, K. Fandrick
- Chemistry
- 20 June 2006
[Structure: see text] Enantioselective nitrone cycloadditions with beta-substituted alpha,beta-unsaturated 2-acyl imidazoles catalyzed by bis(oxazolinyl)pyridine-cerium(IV) triflate complexes 1 have… Expand
Catalytic Enantioselective Pyrrole Alkylations of α,β-Unsaturated 2-Acyl Imidazoles
- David A. Evans and, K. Fandrick
- Chemistry
- 6 May 2006
Enantioselective additions of pyrroles to α,β-unsaturated 2-acyl imidazoles catalyzed by the bis(oxazolinyl)pyridine−scandium(III) triflate complex (1) have been accomplished. The α,β-unsaturated… Expand
A general copper-BINAP-catalyzed asymmetric propargylation of ketones with propargyl boronates.
- K. Fandrick, Daniel R Fandrick, +7 authors C. Senanayake
- Chemistry, Medicine
- Journal of the American Chemical Society
- 22 June 2011
An operationally simple copper-BINAP-catalyzed, highly enantioselective propargylation of ketones is presented. The methodology was developed as an enantioselective process for methyl ethyl ketone… Expand
Transnitrilation from Dimethylmalononitrile to Aryl Grignard and Lithium Reagents: A Practical Method for Aryl Nitrile Synthesis.
- J. T. Reeves, Christian A Malapit, +6 authors C. Senanayake
- Chemistry, Medicine
- Journal of the American Chemical Society
- 15 July 2015
An electrophilic cyanation of aryl Grignard or lithium reagents, generated in situ from the corresponding aryl bromides or iodides, by a transnitrilation with dimethylmalononitrile (DMMN) was… Expand
Insights into chromatographic enantiomeric separation of allenes on cellulose carbamate stationary phase.
- Shengli Ma, Hung-Wei Tsui, +10 authors N. Grinberg
- Chemistry, Medicine
- Journal of chromatography. A
- 3 October 2014
Allenes are cumulenes with three contiguous carbons linked together through double bonds. 1,3-disubstituted allenes are not superimposable on their mirror image; as a consequence they are chiral.… Expand
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