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Elements of regiocontrol in palladium-catalyzed oxidative arene cross-coupling.
By changing the stoichiometric oxidant and modifying the indole N-substituent in palladium-catalyzed oxidative arene cross-coupling reactions, both C2 and C3 oxidative indole arylation can be achie...
Palladium-catalyzed benzene arylation: incorporation of catalytic pivalic acid as a proton shuttle and a key element in catalyst design.
Experimental and computational evidence indicates that the pivalate anion is a key component in the palladium-pivalic acid cocatalyst system, that it lowers the energy of C-H bond cleavage and acts as a catalytic proton shuttle from benzene to the stoichiometric carbonate base. Expand
Catalytic intermolecular direct arylation of perfluorobenzenes.
Penta-, tetra-, tri-, and difluorobenzenes undergo direct arylation with a wide range of arylhalides in high yield and utilize commercially available, air-stable catalyst precursors. Expand
Ruthenium-catalyzed dehydrogenation of ammonia boranes.
It was shown that alkylamine-boranes can serve as a source of H2 in the Ru-catalyzed reduction of ketones and imines in AB and MeAB. Expand
Intramolecular palladium-catalyzed alkane C-H arylation from aryl chlorides.
DFT(B3PW91) calculations demonstrated that C-H activation is the rate-determining step and that the creation of a C(sp(3))-H agostic interaction, increasing the acidity of a geminal C- H bond, is a critical factor for the regiochemistry control. Expand
Direct arylation reactions catalyzed by Pd(OH)2/C: evidence for a soluble palladium catalyst.
[reactions: see text] Palladium hydroxide on carbon (Pearlman's catalyst) effectively catalyzes direct arylation reactions of aryl iodides and bromides, providing excellentExpand
Rhodium-catalyzed coupling reactions of arylboronic acids to olefins in aqueous media.