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Effect of gene disruptions of the TCA cycle on production of succinic acid in Saccharomyces cerevisiae.
Succinate is the main taste component produced by yeasts during sake (Japanese rice wine) fermentation. The pathway leading to accumulation of succinate was examined in liquid culture in the presenceExpand
Bioactive Pigments from Marine Bacteria: Applications and Physiological Roles
Research into natural products from the marine environment, including microorganisms, has rapidly increased over the past two decades. Despite the enormous difficulty in isolating and harvestingExpand
Quorum Sensing Signaling Molecules Involved in the Production of Violacein by Pseudoalteromonas
The production of violacein by Pseudoalteromonas sp. 520P1 has many features of quorum sensing. Signaling molecules were extracted from bacterial culture and subsequently identified asExpand
One of the fumarate reductase isoenzymes from Saccharomyces cerevisiae is encoded by the OSM1 gene.
Soluble fumarate reductase from yeast irreversibly catalyzes the reduction of fumarate to succinate and has noncovalently bound flavin adenine dinucleotide. In yeast, there are two isoenzymes ofExpand
Isolation and Characterization of Two Groups of Novel Marine Bacteria Producing Violacein
Thirteen strains of novel marine bacteria producing a purple pigment were isolated from the Pacific coast of Japan. They were divided into two groups based on their 16S ribosomal RNA gene sequences,Expand
Physiological role of soluble fumarate reductase in redox balancing during anaerobiosis in Saccharomyces cerevisiae.
In Saccharomyces cerevisiae, there are two isoenzymes of fumarate reductase (FRDS1 and FRDS2), encoded by the FRDS and OSM1 genes, respectively. Simultaneous disruption of these two genes results inExpand
Isolation of sake yeast strains possessing various levels of succinate- and/or malate-producing abilities by gene disruption or mutation.
Succinate and malate are the main taste components produced by yeast during sake (Japanese alcohol beverage) fermentation. Sake yeast strains possessing various organic acid productivities wereExpand
Soluble fumarate reductase isoenzymes from Saccharomyces cerevisiae are required for anaerobic growth.
In Saccharomyces cerevisiae, the cytosolic and promitochondrial isoenzymes of fumarate reductase are encoded by the FRDS and OSM1 genes, respectively. The product of the OSM1 gene is reported to beExpand
Evidence for the Presence of a GTP‐Dependent Regulatory Component of Adenylate Cyclase in Myelin from Rat Brain
Abstract: A GTP‐dependent regulatory component of adenylate cyclase was found in myelin from rat brain. The fraction solubilized from myelin contained a component that reconstituted guanineExpand
Enzymatic assay of allantoin in serum using allantoinase and allantoate amidohydrolase.
A new enzymatic assay for specifically measuring allantoin concentration in serum has been developed. The currently used methods for allantoin analysis are time consuming and nonspecific or depend onExpand