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Hypertriglyceridemia as a cardiovascular risk factor.
To determine the relation between plasma triglyceride levels and the risk of incident cardiovascular disease, the semiquantitative techniques of meta-analysis were applied to 17 population-based… Expand
Aristolochic acid-associated urothelial cancer in Taiwan
- C. Chen, K. Dickman, +9 authors A. Grollman
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 9 April 2012
Aristolochic acid, a potent human carcinogen produced by Aristolochia plants, is associated with urothelial carcinoma of the upper urinary tract (UUC). Following metabolic activation, aristolochic… Expand
Product design: Practical methods for the systematic development of new products: Mike Baxter Chapman & Hall, 1995, ISBN 0-412-63230-6, 308pp, £24.99
- K. Edwards
- Materials Science
Effect of genotype on phenotype and mortality in cystic fibrosis: a retrospective cohort study
BACKGROUND Over 1000 mutations of the cystic fibrosis transmembrane conductance regulator gene (CFTR) that cause cystic fibrosis have been identified. We examined the effect of CFTR genotype on… Expand
Family history of diabetes as a potential public health tool.
- Tabitha A. Harrison, L. Hindorff, +4 authors K. Edwards
- American journal of preventive medicine
- 1 February 2003
Given the substantial morbidity and mortality associated with type 2 diabetes, it is important that public health seek ways to delay or prevent the onset of this condition. Risk factors for type 2… Expand
Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid.
Endemic (Balkan) nephropathy is a chronic tubulointerstitial disease frequently accompanied by urothelial cell carcinomas of the upper urinary tract. This disorder has recently been linked to… Expand
APOE ε4 increases risk for dementia in pure synucleinopathies.
OBJECTIVE To test for an association between the apolipoprotein E (APOE) ϵ4 allele and dementias with synucleinopathy. DESIGN Genetic case-control association study. SETTING Academic research. … Expand
Cardiovascular disease mortality in familial forms of hypertriglyceridemia: A 20-year prospective study.
BACKGROUND Familial combined hyperlipidemia (FCHL) and familial hypertriglyceridemia (FHTG) are 2 of the most common familial forms of hyperlipidemia. There is a paucity of prospective data… Expand
Association analysis of MAPT H1 haplotype and subhaplotypes in Parkinson's disease
An inversion polymorphism of approximately 900kb on chromosome 17q21, which includes the microtubule‐associated protein tau (MAPT) gene defines two haplotype clades, H1 and H2. Several small… Expand
SNCA variant associated with Parkinson disease and plasma alpha-synuclein level.
BACKGROUND A functional repeat polymorphism in the SNCA promoter (REP1) conveys susceptibility for Parkinson disease (PD). There is also increasing evidence that single-nucleotide polymorphisms… Expand