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Identification of a Survival-Promoting Peptide in Medium Conditioned by Oxidatively Stressed Cell Lines of Nervous System Origin
A survival-promoting peptide has been purified from medium conditioned by Y79 human retinoblastoma cells and a mouse hippocampal cell line (HN 33.1) exposed to H2O2. A 30 residue synthetic peptideExpand
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Dynamic gene and protein expression patterns of the autism‐associated met receptor tyrosine kinase in the developing mouse forebrain
The establishment of appropriate neural circuitry depends on the coordination of multiple developmental events across space and time. These events include proliferation, migration, differentiation,Expand
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Evidence of cell‐nonautonomous changes in dendrite and dendritic spine morphology in the met‐signaling–deficient mouse forebrain
Human genetic findings and murine neuroanatomical expression mapping have intersected to implicate Met receptor tyrosine kinase signaling in the development of forebrain circuits controlling socialExpand
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Regulation of neocortical interneuron development and the implications for neurodevelopmental disorders
Neurodevelopmental disorders typically have complex endophenotypes, which can include abnormalities in neuronal excitability, processing of complex information, as well as behaviors such as anxietyExpand
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Region‐ and age‐specific deficits in γ‐aminobutyric acidergic neuron development in the telencephalon of the uPAR–/– mouse
We have previously shown that in adult mice with a null mutation in the urokinase‐type plasminogen activator receptor (uPAR) gene, maintained on a C57BL/6J/129Sv background, there is a selective lossExpand
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Patterning and specification of the cerebral cortex.
Regionalization of the cerebral cortex occurs during development by the formation of anatomically and functionally discrete areas of the brain. Descriptive evidence based on expression of moleculesExpand
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Complementary distribution of collagen type IV and the epidermal growth factor receptor in the rat embryonic telencephalon.
We previously identified an interaction between collagen type IV and the EGF receptor that regulates the differentiation of a limbic cortical phenotype in vitro (Ferri and Levitt, 1995). In theExpand
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Disruption of Foxg1 expression by knock-in of Cre recombinase: Effects on the development of the mouse telencephalon
The cre/loxP system is used routinely to manipulate gene expression in the mouse nervous system. In order to delete genes specifically from the telencephalon, the Foxg1-cre line was createdExpand
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Mechanisms specifying area fate in cortex include cell-cycle-dependent decisions and the capacity of progenitors to express phenotype memory.
Progenitor cells in the early developing cerebral cortex produce neurons destined for discrete functional areas in response to specific inductive signals. Using lineage analysis, we show thatExpand
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Regional Differences in Neurotrophin Availability Regulate Selective Expression of VGF in the Developing Limbic Cortex
Gene and protein expression patterns in the cerebral cortex are complex and often change spatially and temporally through development. The signals that regulate these patterns are primarily unknown.Expand
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