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A secreted fluorescent reporter targeted to pituitary growth hormone cells in transgenic mice.
In stable transfection experiments in the GH-producing GC cell line, a construct containing the entire signal peptide and the first 22 residues of human GH linked in frame with enhanced greenExpand
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Growth hormone-releasing hormone (GHRH) neurons in GHRH-enhanced green fluorescent protein transgenic mice: a ventral hypothalamic network.
The hypothalamic GHRH neurons secrete pulses of GHRH to generate episodic GH secretion, but little is known about the mechanisms involved. We have made transgenic mice expressing enhanced greenExpand
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Exploring the consequences of mitochondrial differences arising through hybridization of sunfish.
Previous studies have shown evidence of genomic incompatibility and mitochondrial enzyme dysfunction in hybrids of bluegill (Lepomis macrochirus Rafinesque) and pumpkinseed (Lepomis gibbosusExpand
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Regulation of mitochondrial metabolism during hibernation by reversible suppression of electron transport system enzymes
Small hibernators cycle between periods of torpor, with body temperature (Tb) approximately 5 °C, and interbout euthermia (IBE), where Tb is approximately 37 °C. During entrance into a torpor boutExpand
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Reversible temperature-dependent differences in brown adipose tissue respiration during torpor in a mammalian hibernator.
Although seasonal modifications of brown adipose tissue (BAT) in hibernators are well documented, we know little about functional regulation of BAT in different phases of hibernation. In the 13-linedExpand
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Differential post-translational modification of mitochondrial enzymes corresponds with metabolic suppression during hibernation.
During hibernation, small mammals, including the 13-lined ground squirrel (Ictidomys tridecemlineatus), cycle between two distinct metabolic states: torpor, where metabolic rate is suppressed by >95%Expand
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Regulation of liver mitochondrial metabolism during hibernation by post-translational modification
................................................................................................................... ii ACKNOWLEDGEMENTSExpand
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Hybridization in Sunfish Influences the Muscle Metabolic Phenotype
Hybridization has the potential to exert pleiotropic effects on metabolism. Effects on mitochondrial enzymes may arise through incompatibilities in nuclear- and mitochondrial-encoded subunits of theExpand
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Comparative biochemistry of cytochrome c oxidase in animals.
Cytochrome c oxidase (COX), the terminal enzyme of the electron transport system, is central to aerobic metabolism of animals. Many aspects of its structure and function are highly conserved, yet,Expand
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