K. Downes

Publications41
h-index16
Citations923
Highly Influential Citations50
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Bizarre leiomyomas of the uterus: a comprehensive pathologic study of 24 cases with long-term follow-up.
  • K. Downes, W. Hart
  • Medicine
  • The American journal of surgical pathology
  • 1 November 1997
A series of 24 bizarre (symplastic, pleomorphic) leiomyomas was analyzed to determine their spectrum of gross and microscopic features and to establish their clinical behavior by obtaining long-term… Expand
  • 131
  • 11
Pleomorphic Liposarcoma: A Clinicopathologic Analysis Of 19 Cases
Pleomorphic liposarcoma is a variant of liposarcoma defined morphologically by the presence of pleomorphic lipoblasts. Because of its rarity, there are limited studies with long-term follow-up… Expand
  • 117
  • 8
Transfusion of platelets containing ABO-incompatible plasma: a survey of 3156 North American laboratories.
CONTEXT Hemolytic transfusion reactions due to platelet transfusions containing ABO-incompatible plasma (ie, group O platelets into a non-group O patient) have been reported in the literature.… Expand
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  • 8
  • PDF
Combined deficiency of factor V and factor VIII is due to mutations in either LMAN1 or MCFD2.
Mutations in LMAN1 (ERGIC-53) or MCFD2 cause combined deficiency of factor V and factor VIII (F5F8D). LMAN1 and MCFD2 form a protein complex that functions as a cargo receptor ferrying FV and FVIII… Expand
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Serial measurement of clotting factors in thawed plasma stored for 5 days
The seventeenth edition of Standards for Blood Banks and Transfusion Services1 changed the transfusion expiration time for FFP from no more than 24 hours after thawing to up to 5 days when thawed… Expand
  • 86
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Evolution of surveillance methods for detection of bacterial contamination of platelets in a university hospital, 1991 through 2004
BACKGROUND:  Platelet (PLT) bacterial contamination (PBC) is the most common transfusion‐associated infection. It is important to understand the impact of interventions addressing this problem.
  • 90
  • 3
Relapsed thrombotic thrombocytopenic purpura presenting as an acute cerebrovascular accident
Thrombotic thrombocytopenic purpura (TTP) is an uncommon but severe disorder that classically presents with microangiopathic hemolytic anemia (MAHA), thrombocytopenia, and fluctuating neurological… Expand
  • 52
  • 2
Lack of isohemagglutinin production following minor ABO incompatible unrelated HLA mismatched umbilical cord blood transplantation
While immune hemolysis due to donor isohemagglutinin (IH) production often complicates minor ABO incompatible peripheral blood hematopoietic stem cell transplantation (PBSCT), it is not known if this… Expand
  • 18
  • 2
Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting with Diffusion MR Imaging Changes
SUMMARY: Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) presents with focal or diffuse nonenhancing MR imaging abnormalities in 50% of patients with SREAT during… Expand
  • 32
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Warfarin does not interfere with lupus anticoagulant detection by dilute Russell's viper venom time.
BACKGROUND The dilute Russell's viper venom time (DRVVT) test is part of the diagnostic armamentarium used to detect lupus anticoagulant (LA). When testing patients on warfarin therapy, there is some… Expand
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