• Publications
  • Influence
l-Arginine-Dependent Epigenetic Regulation of Interleukin-10, but Not Transforming Growth Factor-β, Production by Neonatal Regulatory T Lymphocytes
A growing number of diseases in humans, including trauma, certain cancers, and infection, are known to be associated with l-arginine deficiency. In addition, l-arginine must be supplemented by dietExpand
  • 12
  • 3
  • PDF
Overexpression of galectin-3 enhances migration of colon cancer cells related to activation of the K-Ras–Raf–Erk1/2 pathway
BackgroundGalectin-3 has been independently correlated with malignant behavior in human colon cancer. The involvement of galectin-3 in the invasiveness of colon cancer cells remains to be determined.Expand
  • 46
  • 2
l‐Arginine modulates neonatal lymphocyte proliferation through an interleukin‐2 independent pathway
In cases of arginine depletion, lymphocyte proliferation, cytokine production and CD3ζ chain expression are all diminished. In addition to myeloid suppressor cells, polymorphonuclear cells (PMN) alsoExpand
  • 20
  • 1
Aging-dependent DNA hypermethylation and gene expression of GSTM1 involved in T cell differentiation
This study investigated whether aging was associated with epigenetic changes of DNA hypermethylation on immune gene expression and lymphocyte differentiation. We screened CG sites of methylation inExpand
  • 6
  • 1
  • PDF
Complement regulatory protein CD46 induces autophagy against oxidative stress-mediated apoptosis in normal and asthmatic airway epithelium
Autophagy plays a major role in defending against oxidative stress in respiratory epithelial cells. The complement regulatory protein CD46 can enhance autophagy and decrease local complementExpand
  • 10
  • 1
Comparison of the Functional microRNA Expression in Immune Cell Subsets of Neonates and Adults
Diversity of biological molecules in newborn and adult immune cells contributes to differences in cell function and atopic properties. Micro RNAs (miRNAs) are reported to involve in the regulation ofExpand
  • 16
  • PDF
Functions and therapeutic targets of Siglec-mediated infections, inflammations and cancers.
Siglecs, sialic acid (SA)-binding immunoglobulin (Ig)-like lectins, belong to a family of Ig-like lectins. All Siglecs have at least two domains including an extracellular domain with variable (V)Expand
  • 5
Intravenous immunoglobulin therapy enhances suppressive regulatory T cells and decreases innate lymphoid cells in children with immune thrombocytopenia
This study aimed to investigate the relationship between CD4+ regulatory T cells (Tregs) and innate lymphoid cells (ILCs) in children with primary immune thrombocytopenia (ITP) undergoing high‐doseExpand
  • 4