• Publications
  • Influence
The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the
The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and theExpand
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
TLDR
It is demonstrated that insulin resistance and DM associate with reduced expression of multiple nuclear respiratory factor-1 (NRF-1)-dependent genes encoding key enzymes in oxidative metabolism and mitochondrial function. Expand
The diagnosis and management of non‐alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the
TLDR
This is a practice guideline for clinicians rather than a review article and interested readers can refer to several comprehensive reviews published recently. Expand
The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and
The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, andExpand
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
Abstract This guidance provides a data-supported approach to the diagnostic, therapeutic, and preventive aspects of NAFLD care. A "Guidance" document is different from a "Guideline." Guidelines areExpand
A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis.
TLDR
In this proof-of-concept study, the administration of pioglitazone led to metabolic and histologic improvement in subjects with nonalcoholic steatohepatitis and larger controlled trials of longer duration are warranted to assess the long-term clinical benefit. Expand
Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications.
  • K. Cusi
  • Medicine
  • Gastroenterology
  • 1 April 2012
TLDR
Treatments that rescue the liver from lipotoxicity by restoring adipose tissue insulin sensitivity or preventing activation of inflammatory pathways and oxidative stress hold promise in the treatment of NAFLD, although their long-term safety and efficacy remain to be established. Expand
Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes
TLDR
Gene expression profiling indicated that both isoforms of the adiponectin receptor play a role in the insulin-sensitising effect of adip onectin in human skeletal muscle. Expand
Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects.
TLDR
Both LF and VAT, but not SAT, were correlated significantly (P < .05) with basal hepatic IR and residual EGP during insulin clamp, and both VAT and LF are associated with hepaticIR. Expand
...
1
2
3
4
5
...