K. Chin

Publications68
h-index21
Citations2,648
Highly Influential Citations79
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Computed tomographic measurements of airway dimensions and emphysema in smokers. Correlation with lung function.
Chronic obstructive pulmonary disease (COPD) is characterized by the presence of airflow obstruction caused by emphysema or airway narrowing, or both. Low attenuation areas (LAA) on computed… Expand
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Changes in intra-abdominal visceral fat and serum leptin levels in patients with obstructive sleep apnea syndrome following nasal continuous positive airway pressure therapy.
BACKGROUND Obstructive sleep apnea syndrome (OSAS) is a common disorder in obese subjects. Visceral fat accumulation (VFA) is a better predictor of coronary heart disease than body mass index. Leptin… Expand
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  • 14
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Complexity of terminal airspace geometry assessed by lung computed tomography in normal subjects and patients with chronic obstructive pulmonary disease.
Increases in the low attenuation areas (LAA) of chest x-ray computed tomography images in patients with chronic obstructive pulmonary disease (COPD) have been reported to reflect the development of… Expand
  • 310
  • 8
  • PDF
The nocturnal secretion of cardiac natriuretic peptides during obstructive sleep apnoea and its response to therapy with nasal continuous positive airway pressure
The nocturnal secretion profile of the newly identified natriuretic peptide (NP), brain natriuretic peptide (BNP), was studied in 14 patients with obstructive sleep apnoea syndrome (OSAS) (apnoea… Expand
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Effects of nasal continuous positive airway pressure on soluble cell adhesion molecules in patients with obstructive sleep apnea syndrome.
PURPOSE Obstructive sleep apnea syndrome is common in middle-aged men and may be associated with an increased risk of cardiovascular disease. We investigated the effect of nasal continuous positive… Expand
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CCM-3/STRIPAK promotes seamless tube extension through endocytic recycling.
The mechanisms governing apical membrane assembly during biological tube development are poorly understood. Here, we show that extension of the C. elegans excretory canal requires cerebral cavernous… Expand
  • 54
  • 3
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Effects of NCPAP therapy on fibrinogen levels in obstructive sleep apnea syndrome.
  • K. Chin, M. Ohi, +5 authors K. Kuno
  • Medicine
  • American journal of respiratory and critical care…
  • 1 June 1996
In patients with obstructive sleep apnea syndrome (OSAS), the blood coagulation system may contribute to an increased risk of cardiovascular events, which occur most frequently in the morning. Nasal… Expand
  • 236
  • 2
Improvement of factor VII clotting activity following long-term NCPAP treatment in obstructive sleep apnoea syndrome.
  • K. Chin, H. Kita, +6 authors M. Ohi
  • Medicine
  • QJM : monthly journal of the Association of…
  • 1 September 1998
Obstructive sleep apnoea syndrome (OSAS) is a very common disorder. Patients with OSAS are at an increased risk for cardiovascular events. It has also been reported that a 25% rise in factor VII… Expand
  • 43
  • 1
Increase in bilirubin levels of patients with obstructive sleep apnea in the morning--a possible explanation of induced heme oxygenase-1.
STUDY OBJECTIVES In the absence of heme oxygenase-1 (HO-1), which catalyzes the oxidation of heme to generate carbon monoxide and indirect bilirubin, hypoxia induces severe right ventricular dilation… Expand
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Heat shock protein 72 level decreases during sleep in patients with obstructive sleep apnea syndrome.
Patients with obstructive sleep apnea syndrome (OSAS) suffer from stresses related to repetitive apneas during sleep. To examine whether the level of 72 kDa heat shock protein (HSP72) increases… Expand
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  • 1