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Anti-AIDS agents--XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues.
Bioactivity-directed fractionation of an ethanolic extract of the stems of Kadsura interior led to the isolation and identification of 12 known lignans (1-12). Seven of these compounds (1, 6, 8-12)Expand
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Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior.
Two new lignans, interiotherins A (1) and B (2), along with two known lignans, angeloylgomisin R (3) and schisantherin D (4), were isolated from Kadsura interior. Their structures andExpand
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Anti-AIDS agents, 4. Tripterifordin, a novel anti-HIV principle from Tripterygium wilfordii: isolation and structural elucidation.
A new kaurane-type diterpene lactone, tripterifordin [1], has been isolated from the roots of Tripterygium wilfordii. The structure of 1 was elucidated by spectroscopic methods, including theExpand
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Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra.
Three flavonols, 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone [1], 5,4'-dihydroxy-3,6,7,8,3'-pentamethoxyflavone [2], and quercetin 3-O-beta-D-glucopyranosyl-7-O-alpha-L-rhamnopyranoside [3], wereExpand
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Northalifoline, a New Isoquinolone Alkaloid from the Pedicels of Lindera megaphylla
A new isoquinolone alkaloid, northalifoline [1] was obtained from the pedicels of Lindera megaphylla along with six other alkaloids, namely, (+)-O-methylbulbocapnine [2}, (+)-dicentrine [3],Expand
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The isolation and structural elucidation of four novel triterpene lactones, pseudolarolides A, B, C, and D, from Pseudolarix kaempferi.
Four novel triterpene lactones, pseudolarolides A [1], B [2], C [3], and D [4], were isolated from the seeds of Pseudolarix kaempferi. Their structures and stereochemistry were elucidated fromExpand
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Anti-aids agents, 6. Salaspermic acid, an anti-HIV principle from Tripterygium wilfordii, and the structure-activity correlation with its related compounds.
Salaspermic acid [1], an inhibitor of HIV reverse transcriptase and HIV replication in H9 lymphocyte cells, was isolated from the roots of Tripterygium wilfordii for the first time. The structure ofExpand
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Three new sesquiterpene glycosides from Dendrobium nobile with immunomodulatory activity.
Dendroside A (1) and dendronobilosides A and B (2 and 3), three new sesquiterpene glycosides, have been isolated from the stems of Dendrobium nobile, a plant used in Chinese traditional medicine.Expand
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Modulation of drug-metabolizing enzymes by extracts of a herbal medicine Evodia rutaecarpa in C57BL/6J mice.
Evodia rutaecarpa is a traditional Chinese medicine used for the treatment of gastrointestinal disorders and headache. To assess the possible drug interactions, effects of methanol and aqueousExpand
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Flavonoids from Evodiae Fructus
Three alkaloids, three flavonoids and one limonoid were isolated from the dried fruit of Evodia rutaecarpa (Wu-Chu-Yu) (Rutacease), which contains active principles and has been used in ChineseExpand
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