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Anti-AIDS agents--XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues.
- D. Chen, S. Zhang, +7 authors K. Lee
- Chemistry, Medicine
- Bioorganic & medicinal chemistry
- 1 August 1997
Bioactivity-directed fractionation of an ethanolic extract of the stems of Kadsura interior led to the isolation and identification of 12 known lignans (1-12). Seven of these compounds (1, 6, 8-12)… Expand
Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior.
Two new lignans, interiotherins A (1) and B (2), along with two known lignans, angeloylgomisin R (3) and schisantherin D (4), were isolated from Kadsura interior. Their structures and… Expand
Anti-AIDS agents, 4. Tripterifordin, a novel anti-HIV principle from Tripterygium wilfordii: isolation and structural elucidation.
A new kaurane-type diterpene lactone, tripterifordin , has been isolated from the roots of Tripterygium wilfordii. The structure of 1 was elucidated by spectroscopic methods, including the… Expand
Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra.
Three flavonols, 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone , 5,4'-dihydroxy-3,6,7,8,3'-pentamethoxyflavone , and quercetin 3-O-beta-D-glucopyranosyl-7-O-alpha-L-rhamnopyranoside , were… Expand
Northalifoline, a New Isoquinolone Alkaloid from the Pedicels of Lindera megaphylla
A new isoquinolone alkaloid, northalifoline  was obtained from the pedicels of Lindera megaphylla along with six other alkaloids, namely, (+)-O-methylbulbocapnine [2}, (+)-dicentrine ,… Expand
The isolation and structural elucidation of four novel triterpene lactones, pseudolarolides A, B, C, and D, from Pseudolarix kaempferi.
Four novel triterpene lactones, pseudolarolides A , B , C , and D , were isolated from the seeds of Pseudolarix kaempferi. Their structures and stereochemistry were elucidated from… Expand
Anti-aids agents, 6. Salaspermic acid, an anti-HIV principle from Tripterygium wilfordii, and the structure-activity correlation with its related compounds.
Salaspermic acid , an inhibitor of HIV reverse transcriptase and HIV replication in H9 lymphocyte cells, was isolated from the roots of Tripterygium wilfordii for the first time. The structure of… Expand
Three new sesquiterpene glycosides from Dendrobium nobile with immunomodulatory activity.
Dendroside A (1) and dendronobilosides A and B (2 and 3), three new sesquiterpene glycosides, have been isolated from the stems of Dendrobium nobile, a plant used in Chinese traditional medicine.… Expand
Modulation of drug-metabolizing enzymes by extracts of a herbal medicine Evodia rutaecarpa in C57BL/6J mice.
- Y. Ueng, Han-Chieh Ko, C. Chen, Jong-Jing Wang, K. Chen
- Chemistry, Medicine
- Life sciences
- 2 August 2002
Evodia rutaecarpa is a traditional Chinese medicine used for the treatment of gastrointestinal disorders and headache. To assess the possible drug interactions, effects of methanol and aqueous… Expand
Flavonoids from Evodiae Fructus
Three alkaloids, three flavonoids and one limonoid were isolated from the dried fruit of Evodia rutaecarpa (Wu-Chu-Yu) (Rutacease), which contains active principles and has been used in Chinese… Expand