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In vitro and in vivo toxicological study of the Pterodon pubescens seed oil.
The oil of Pterodon pubescens seeds (PpSO) is known for its cercaricidal and anti-inflammatory effects. Its anti-rheumatic activity was recently reported using mice with collagen II-induced arthritisExpand
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In vitro and in vivo toxicological evaluation of extract and fractions from Baccharis trimera with anti-inflammatory activity.
ETHNOPHARMACOLOGICAL RELEVANCE Baccharis trimera (Less) DC. (Asteraceae), popularly known in Brazil as "carqueja", have been used in folk medicine to treat gastrointestinal, hepatic and renalExpand
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Successful treatment of collagen‐induced arthritis in mice with a hydroalcohol extract of seeds of Pterodon pubescens
The antiarthritic effect of a hydroalcohol extract of Pterodon pubescens (HEPp) seeds was tested using collagen‐induced arthritis (CIA) in DBA1/J mice treated with daily oral doses of HEPp inExpand
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Acute and topic anti‐edematogenic fractions isolated from the seeds of Pterodon pubescens
We previously demonstrated that alcoholic extracts from Pterodon pubescens Benth. (Sucupira branca, Leguminosae) seeds exhibit anti‐arthritic activity. In the present work we show that the oleaginousExpand
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Anti-arthritic effect and subacute toxicological evaluation of Baccharis genistelloides aqueous extract.
This work studies the potential subacute toxicological effects of the aqueous extract of Baccharis genistelloides (AEBg) and demonstrates a new anti-arthritic therapeutic effect. The treatment of theExpand
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Trypanosomatid essential metabolic pathway: new approaches about heme fate in Trypanosoma cruzi.
Trypanosoma cruzi, the causal agent of Chagas disease, has a complex life cycle and depends on hosts for its nutritional needs. Our group has investigated heme (Fe-protoporphyrin IX) internalizationExpand
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In Vitro Antileukemic Activity of Xanthosoma sagittifolium (Taioba) Leaf Extract
Xanthosoma sagittifolium Schott is a herb of the Araceae family, popularly known as taioba, which is consumed as food in some regions of Brazil, Africa, and Asia. This species has already beenExpand
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Hypoglycemic Effect of Bumelia sartorum Polyphenolic Rich Extracts
Bumelia sartorum (Sapotaceae) is used ethnomedicinally for treatment of several diseases, including diabetes mellitus. The aim of this work was to investigate the hypoglycemic effect of B. sartorumExpand
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Proliferation and Differentiation of Trypanosoma cruzi inside Its Vector Have a New Trigger: Redox Status
Trypanosoma cruzi proliferate and differentiate inside different compartments of triatomines gut that is the first environment encountered by T. cruzi. Due to its complex life cycle, the parasite isExpand
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Subacute toxicity evaluation of a hydroalcoholic extract of Pterodon pubescens seeds in mice with collagen-induced arthritis.
When the immune system is stimulated there is a concomitant decrease in drug biotransformation and elimination that may results in unwanted drug response and toxic side effects. We investigated theExpand
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