• Publications
  • Influence
Fibulin-3 promoter methylation alters the invasive behavior of non-small cell lung cancer cell lines via MMP-7 and MMP-2 regulation.
Fibulin-3, an extracellular glycoprotein, has been suggested as having functions in tissue regeneration and organogenesis. However, its role in cancer remains unclear. We showExpand
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PTEN/pAkt/p53 signaling pathway correlates with the radioresponse of non-small cell lung cancer.
The sensitivity or resistance of cancer cells and normal tissues to ionizing radiation plays an important role in the clinical setting of lung cancer treatment. However, to date the exact molecularExpand
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Knockdown of the Dickkopf 3 gene induces apoptosis in a lung adenocarcinoma.
The expression of the Wnt-antagonist Dickkopf gene (DKK) is downregulated in several types of tumors as a consequence of epigenetic DNA modification; four DKK members, DKK1, DKK2, DKK3, and DKK4,Expand
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  • Open Access
Ganoderma lucidum extract protects DNA from strand breakage caused by hydroxyl radical and UV irradiation.
  • K. C. Kim, I. G. Kim
  • Biology, Medicine
  • International journal of molecular medicine
  • 1 September 1999
The fruit bodies of Ganoderma lucidum have been used for the prevention and treatment of various diseases in the Orient. Its antitumor and immune enhancing properties, along with no cytotoxicity,Expand
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Enhanced induction of mitochondrial damage and apoptosis in human leukemia HL-60 cells by the Ganoderma lucidum and Duchesnea chrysantha extracts.
Combined treatment with the medicinal mushroom Ganoderma lucidum and the herb Duchesnea chrysantha extracts (GDE) causes a synergistic induction of mitochondrial damage and apoptosis in HL-60 cells.Expand
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NAD-dependent malate dehydrogenase protects against oxidative damage in Escherichia coli K-12 through the action of oxaloacetate.
Reactive oxygen species including hydrogen peroxide (H(2)O(2)) and hydroxyl radical (OH) can be generated by ionizing radiation and has the potential to induce diseases. We provide the evidence thatExpand
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SM22α-induced activation of p16INK4a/retinoblastoma pathway promotes cellular senescence caused by a subclinical dose of γ-radiation and doxorubicin in HepG2 cells.
Smooth muscle protein 22-alpha (SM22α) is known as a transformation- and shape change-sensitive actin cross-linking protein found in smooth muscle tissue and fibroblasts; however, its functional roleExpand
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Spontaneous liberation of intracellular polyhydroxybutyrate granules in Escherichia coli.
Despite receiving much attention as a biodegradable substitute for conventional non-biodegradable plastics, the commercial use of polyhydroxybutyrate (PHB) remains limited because of its highExpand
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Screening of estrogenic and antiestrogenic activities from medicinal plants.
The medicinal plant extracts commercially used in Asia were screened for their estrogenic and antiestrogenic activities in a recombinant yeast system featuring both a human estrogen receptor (ER)Expand
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Thioredoxin overexpression in HT‐1080 cells induced cellular senescence and sensitization to gamma radiation
An increment of thioredoxin‐1 (TRX) is observed in many human primary cancers and appears to contribute to an increase of cell growth and a resistance to chemotherapy. On the contrary, when TRX wasExpand
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