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An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management.
TLDR
This document represents the current state of knowledge regarding idiopathic pulmonary fibrosis, and contains sections on definition and epidemiology, risk factors, diagnosis, natural history, staging and prognosis, treatment, and monitoring disease course. Expand
An official American Thoracic Society/European Respiratory Society statement: Update of the international multidisciplinary classification of the idiopathic interstitial pneumonias.
TLDR
This update is a supplement to the previous 2002 IIP classification document and outlines advances in the past decade and potential areas for future investigation. Expand
Diagnosis of Idiopathic Pulmonary Fibrosis. An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline
TLDR
The guideline panel provided recommendations related to the diagnosis of IPF, including a conditional recommendation for multidisciplinary discussion and a strong recommendation against measurement of serum biomarkers for the sole purpose of distinguishing IPF from other ILDs. Expand
An official European Respiratory Society/American Thoracic Society research statement: interstitial pneumonia with autoimmune features
TLDR
A sound platform has been provided from which to launch the requisite future research investigations of a more uniform cohort, and nomenclature and classification criteria for patients with IIP and autoimmune features are provided. Expand
Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis.
TLDR
In patients with idiopathic pulmonary fibrosis, BIBF 1120 at a dose of 150 mg twice daily, as compared with placebo, was associated with a trend toward a reduction in the decline in lung function, with fewer acute exacerbations and preserved quality of life. Expand
Diagnostic criteria for idiopathic pulmonary fibrosis: a Fleischner Society White Paper.
TLDR
An updated approach to the diagnosis of idiopathic pulmonary fibrosis is provided, based on a systematic search of the medical literature and the expert opinion of members of the Fleischner Society. Expand
Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis
TLDR
The results suggest that genes involved in host defense, cell-cell adhesion and DNA repair contribute to risk of fibrotic IIPs. Expand
A common MUC5B promoter polymorphism and pulmonary fibrosis.
TLDR
The findings suggest that dysregulated MUC5B expression in the lung may be involved in the pathogenesis of pulmonary fibrosis, and a common polymorphism in the promoter of M UC5B is associated with familial interstitial pneumonia and idiopathic pulmonary fibrot. Expand
An official American Thoracic Society clinical practice guideline: the clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease.
TLDR
Recommendations for the performance and processing of BAL, as well as the interpretation of BAL findings, were formulated by the committee and frequently provide useful information for the diagnostic evaluation of patients with suspected ILD. Expand
Acute Exacerbation of Idiopathic Pulmonary Fibrosis. An International Working Group Report.
TLDR
To better reflect the current state of knowledge and improve the feasibility of future research into its etiology and treatment, the working group proposes a new conceptual framework for acute respiratory deterioration in idiopathic pulmonary fibrosis and a revised definition and diagnostic criteria for acute exacerbation. Expand
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