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Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2.
BACKGROUND/AIMS To elucidate the role of systemic inflammation in nonalcoholic fatty liver disease (NAFLD). METHODS Serum samples in 47 patients with histologically verified NAFLD (22 with simpleExpand
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The effects of acute and chronic exercise on PGC‐1α, irisin and browning of subcutaneous adipose tissue in humans
Irisin was first identified as a peroxisome proliferator‐activated receptor γ co‐activator‐1α (PGC‐1α) dependent myokine with the potential to induce murine brown‐fat‐like development of whiteExpand
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Impact of ethnicity on gestational diabetes identified with the WHO and the modified International Association of Diabetes and Pregnancy Study Groups criteria: a population-based cohort study
Objective The International Association of Diabetes and Pregnancy Study Groups (IADPSG) recently proposed new criteria for diagnosing gestational diabetes mellitus (GDM). We compared prevalenceExpand
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A comparison of the health-related quality of life in patients with diabetic foot ulcers, with a diabetes group and a nondiabetes group from the general population
Objective:The aim of this study was to describe health-related quality-of-life (HRQL) in patients with diabetic foot ulcers by comparing their HRQL with that of a sample from the general populationExpand
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Ethnicity and sex are strong determinants of diabetes in an urban Western society: implications for prevention
Aims/hypothesisThis study was conducted to investigate the prevalence of diabetes and its association with ethnicity and sex, to identify subgroups at special risk.MethodsWe performed aExpand
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Weight gain, total fat gain and regional fat gain during pregnancy and the association with gestational diabetes: a population-based cohort study
Objective:In a multi-ethnic population-based study, we investigate the change in indicators of adiposity (being weight gain and gain of total fat, truncal fat and mean skinfold thickness) from earlyExpand
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Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes.
A time-delayed fluorescence immunoassay was developed for the determination of serum levels of methylglyoxal (MG)-derived hydroimidazolone using a monoclonal antiserum raised againstExpand
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Effect of rhEPO administration on serum levels of sTfR and cycling performance.
PURPOSE We assessed the possibility of using soluble transferrin receptor (sTfR) as an indicator of doping with recombinant erythropoietin (rhEPO). METHODS A double-blind, placebo-controlled studyExpand
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Lower Risk of Heart Failure and Death in Patients Initiated on Sodium-Glucose Cotransporter-2 Inhibitors Versus Other Glucose-Lowering Drugs
Background: Reduction in cardiovascular death and hospitalization for heart failure (HHF) was recently reported with the sodium-glucose cotransporter-2 inhibitor (SGLT-2i) empagliflozin in patientsExpand
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The level of cardiovascular risk factors in bipolar disorder equals that of schizophrenia: a comparative study.
OBJECTIVE In schizophrenia, increased rates of somatic mortality have been shown to correspond with a high prevalence of cardiovascular risk factors, including smoking and the metabolic syndrome. InExpand
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