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Comparison of dementia with Lewy bodies to Alzheimer's disease and Parkinson's disease with dementia
- Enrique Noé, K. Marder, K. Bell, D. Jacobs, J. Manly, Y. Stern
- Psychology, Medicine
- Movement disorders : official journal of the…
- 1 January 2004
We compared the clinical and neuropsychological pattern of dementia with Lewy bodies (DLB) to Alzheimer's disease (AD) and Parkinson's disease with dementia (PD‐d). Sixteen patients clinically… Expand
Association of life activities with cerebral blood flow in Alzheimer disease: implications for the cognitive reserve hypothesis.
BACKGROUND Regional cerebral blood flow (CBF), a good indirect index of cerebral pathologic changes in Alzheimer disease (AD), is more severely reduced in patients with higher educational attainment… Expand
Neuropsychological detection and characterization of preclinical Alzheimer's disease
- D. M. Jacobs, M. Sano, G. Dooneief, K. Marder, K. Bell, Y. Stern
- Psychology, Medicine
- 1 May 1995
Article abstract—We attempted to characterize the changes in cognition associated with the earliest, or preclinical, stages of Alzheimer's disease (AD) by administering a comprehensive… Expand
A randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease
Background: Lowering cholesterol is associated with reduced CNS amyloid deposition and increased dietary cholesterol increases amyloid accumulation in animal studies. Epidemiologic data suggest that… Expand
Cognitive function in nondemented older women who took estrogen after menopause
Investigations of the effects of estrogen replacement on cognitive function in healthy older women have yielded disparate results. We evaluated the relationship between a history of estrogen use and… Expand
Plasma amyloid β‐peptide 1–42 and incipient Alzheimer's disease
Mutations in the amyloid precursor protein and presenilin 1 and 2 genes result in elevated plasma levels of the amyloid β‐peptide species terminating at amino acid residue 42 (Aβ1–42). In a… Expand
An estimate of the incidence of depression in idiopathic Parkinson's disease.
- G. Dooneief, E. Mirabello, K. Bell, K. Marder, Y. Stern, R. Mayeux
- Archives of neurology
- 1 March 1992
Estimates of the prevalence of depression in idiopathic Parkinson's disease vary, but have been greater than in most comparison groups. In a survey of patients with Parkinson's disease (N = 339), the… Expand
Truth and investment: lies are told to those who care.
Participants discussed paintings they liked and disliked with artists who were or were not personally invested in them. Participants were urged to be honest or polite or were given no special… Expand
Clinical characteristics of a family with chromosome 17‐linked disinhibition‐dementia‐ parkinsonism‐amyotrophy complex
We studied the clinical features, pathology, and molecular genetics of a family (Mo) with an autosomal dominant disinhibition, frontal lobe dementia, parkinsonism, and amyotrophy. We examined seven… Expand
Double-blind parallel design pilot study of acetyl levocarnitine in patients with Alzheimer's disease.
Acetyl levocarnitine hydrochloride has been reported to retard dementia in patients with Alzheimer's disease. In a double-blind, parallel design, placebo-controlled pilot study of 30 mild to… Expand