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- Publications
- Influence
Oxytocin and Vasopressin Agonists and Antagonists as Research Tools and Potential Therapeutics
- M. Manning, A. Misicka, +7 authors G. Guillon
- Biology, Medicine
- Journal of neuroendocrinology
- 1 April 2012
We recently reviewed the status of peptide and nonpeptide agonists and antagonists for the V1a, V1b and V2 receptors for arginine vasopressin (AVP) and the oxytocin receptor for oxytocin (OT). In the… Expand
125I-labelled d(CH2)5[Tyr(Me)2,Thr4,Tyr-NH2(9)]OVT: a selective oxytocin receptor ligand.
- J. Elands, C. Barberis, +5 authors W. H. Sawyer
- Biology, Medicine
- European journal of pharmacology
- 1 March 1988
An oxytocic antagonist, [1-(beta-mercapto-beta, beta-cyclopentamethylenepropionic acid,2-O-methyltyrosine,4-threonine, 8-ornithine,9-tyrosylamide]vasotocin (d(CH2)5[Tyr(Me)2, Thr4,Tyr-NH2(9)]OVT… Expand
Solid-phase synthesis of 16 potent (selective and nonselective) in vivo antagonists of oxytocin.
- M. Manning, M. Kruszynski, +7 authors W. H. Sawyer
- Chemistry, Medicine
- Journal of medicinal chemistry
- 1 February 1989
We describe the synthesis and some pharmacological properties of 16 new in vivo antagonists of oxytocin. These are based on modifications of three peptides: A, B, and C. A is our previously reported… Expand
Characterization of a novel, linear radioiodinated vasopressin antagonist: an excellent radioligand for vasopressin V1a receptors.
- C. Barbeis, M. Balestre, +7 authors S. Schlosser
- Chemistry, Medicine
- Neuroendocrinology
- 1 July 1995
We report on the pharmacological properties of a potent and selective linear vasopressin (AVP) V1a receptor antagonist HO-Phenylacetyl1-D-Tyr(Me)2-Phe3-Gln4-Asn5-Arg6-Pro7-Arg8-NH2 (HO-LVA).… Expand
Synthesis and some pharmacological properties of potent and selective antagonists of the vasopressor (V1-receptor) response to arginine-vasopressin.
- M. Manning, S. Stoev, +4 authors W. H. Sawyer
- Chemistry, Medicine
- Journal of medicinal chemistry
- 24 January 1992
We report the solid-phase synthesis of eight position-9-modified analogues of the potent V1-receptor antagonist of arginine-vasopressin, [1-(beta-mercapto-beta,beta-pentamethylenepropionic… Expand
Design and synthesis of potent in vivo antagonists of oxytocin.
- K. Bańkowski, M. Manning, J. Seto, J. Haldar, W. H. Sawyer
- Chemistry, Medicine
- International journal of peptide and protein…
- 12 January 2009
We have previously shown that the substitution of 8-ornithine and 2-O-methyltyrosine alone and in combination in [1-deaminopenicillamine] oxytocin (dPOT) brought about enhancements in antagonistic… Expand
Advances in the design of selective antagonists, potential tocolytics, and radioiodinated ligands for oxytocin receptors.
- M. Manning, L. Cheng, +6 authors W. Y. Chan
- Medicine
- Advances in experimental medicine and biology
- 1995
Despite intensive efforts over three decades in many laboratories, attempts to design peptide antagonists of oxytocin (OT) which are more selective for OT uterine receptors than for vasopressin… Expand
Euro Area Fiscal Stance
- K. Bańkowski, M. Ferdinandusse, Maria Grazia Attinasi, Cristina D. Checherita-Westphal, Georgios Palaiodimos, M. Campos
- Economics
- 25 January 2017
This paper analyses the appropriateness of the euro area fiscal stance. In this context, the paper presents the relevant definitions and how the euro area fiscal stance has evolved over time.… Expand
Design of potent antagonists of the vasopressor response to arginine-vasopressin.
- K. Bańkowski, M. Manning, J. Haldar, W. H. Sawyer
- Chemistry, Medicine
- Journal of medicinal chemistry
- 1 September 1978
As part of a program in which we are attempting to design and synthesize antagonists of the vasopressor response to arginine-vasopressin (AVP), [1-deaminopenicillamine]arginine-vasopressin (dPAVP),… Expand
The design of effective in vivo antagonists of rat uterus and milk ejection responses to oxytocin.
- W. H. Sawyer, J. Haldar, +5 authors M. Manning
- Biology, Medicine
- Endocrinology
- 1980
Several new synthetic analogs of the oxytocin antagonist [1-deaminopenicillamine]oxytocin have been prepared and tested for their abilities to inhibit responses to oxytocin by the isolated rat uterus… Expand