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Lipid peroxidation and free radical scavengers in thyroid dysfunction in the rat: a possible mechanism of injury to heart and skeletal muscle in hyperthyroidism.
This study was designed to determine if peroxidation of biomembrane lipid and the protective system can be modified by the change in oxidative metabolism induced by thyroid dysfunction. The freeExpand
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Serum antioxidant status in streptozotocin-induced diabetic rat.
To determine whether decrease in serum antioxidants contributes to the increased oxidative stress, we measured the antioxidant activity (AOA), total peroxyl radical-trapping antioxidant parameterExpand
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Oxidative muscular injury and its relevance to hyperthyroidism.
In experimental hyperthyroidism, acceleration of lipid peroxidation occurs in heart and slow-oxidative muscles, suggesting the contribution of reactive oxygen species to the muscular injury caused byExpand
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Intense Superoxide Dismutase‐1 Immunoreactivity in Intracytoplasmic Hyaline Inclusions of Familial Amyotrophic Lateral Sclerosis with Posterior Column Involvement
This report concerns retrospective immunohistochemical and immunoelectron microscopic studies on superoxide dismutase-1 (SOD1) in intracytoplasmic hyaline inclusions (IHIs) of the anterior horn cellsExpand
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Immunohistochemical study on superoxide dismutases in spinal cords from autopsied patients with amyotrophic lateral sclerosis.
A role mutations in the superoxide dismutase (SOD)-1 gene in the pathogenesis of amyotrophic lateral sclerosis (ALS) has been discussed. To investigate immunohistochemical alterations of SOD in theExpand
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Decrease in serum adiponectin level due to obesity and visceral fat accumulation in children.
OBJECTIVE To determine whether serum adiponectin is decreased in obesity and is restored toward normal level after treatment in children. RESEARCH METHODS AND PROCEDURES Subjects were 53 JapaneseExpand
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Antioxidants in the serum of children with insulin-dependent diabetes mellitus.
To determine whether alteration in serum antioxidant status is related to the increased oxidative stress as a cause of diabetic angiopathy, we measured both the antioxidant activity (AOA) and totalExpand
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High molecular weight, rather than total, adiponectin levels better reflect metabolic abnormalities associated with childhood obesity.
CONTEXT Japanese are prone to obesity-induced metabolic derangement, which is linked to serum adipocytokine profile even in children. OBJECTIVE The objective of the study was to determine whetherExpand
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Pathological characterization of astrocytic hyaline inclusions in familial amyotrophic lateral sclerosis.
To clarify the pathological characteristics of astrocytic hyaline inclusions (Ast-HIs) in patients with familial amyotrophic lateral sclerosis (FALS) with neuronal Lewy-body-like hyaline inclusionsExpand
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Rat superoxide dismutases. Purification, labeling, immunoassay, and tissue concentration.
  • K. Asayama, I. Burr
  • Medicine, Chemistry
  • The Journal of biological chemistry
  • 25 February 1985
This study determines the validity of utilizing radioimmunoassay of CuZn and Mn superoxide dismutase in the rat for defining mechanism of control over mammalian tissue superoxide dismutaseExpand
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