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Comparison of the gut microbiota of people in France and Saudi Arabia
TLDR
French individuals had significantly higher richness and biodiversity compared with Saudis at all the OTU cutoffs (P<0.05), and microbiota differences between obese and normal weight French were not similar to those between obese or normal weight Saudis.
Phenolics from Garcinia mangostana alleviate exaggerated vasoconstriction in metabolic syndrome through direct vasodilatation and nitric oxide generation
TLDR
The phenolic compounds 2, 4, and 5 ameliorated the exaggerated vasoconstriction in MetS aortae through vasodilatation-NO generation mechanism.
Mangostanaxanthones III and IV: advanced glycation end-product inhibitors from the pericarp of Garcinia mangostana
TLDR
All of the isolated xanthones significantly inhibited both sugar (ribose) and dicarbonyl compound (methylglyoxal)-induced protein glycation in a dose-dependent manner, explained by the ability of the isolate to inhibit protein oxidation.
Phenolics from Garcinia mangostana Inhibit Advanced Glycation Endproducts Formation: Effect on Amadori Products, Cross-Linked Structures and Protein Thiols
TLDR
Investigation of the inhibitory effect of bioactive metabolites isolated from fruit hulls of Garcinia mangostana on AGE formation found phenolic compounds 1–4 inhibited AGEs formation at the levels of Amadori product and protein aggregation formation through saving protein thiol.
Volatile oil profile of some lamiaceous plants growing in Saudi Arabia and their biological activities
TLDR
A comparative investigation of hydro-distilled essential oils from aerial parts of Mentha longifolia, Mentha microphylla, and Teucrium polium growing in Al Madinah Al Munawwarah, Saudi Arabia, was carried out, finding that MA essential oils exhibited antifungal activities towards Candida krusei and C. glabrata.
Chemical constituents and biological investigations of the aerial parts of Egyptian Clerodendrum inerme
Abstract B-friedoolean-5-ene-3- β -ol ( 1 ), β -sitosterol ( 2 ), stigmasta-5,22,25-trien-3- β -ol ( 3 ), betulinic acid ( 4 ), and 5-hydroxy-6,7,4′-trimethoxyflavone ( 5 ) were isolated from the
Bioactive Hydantoin Alkaloids from the Red Sea Marine Sponge Hemimycale arabica
TLDR
Hemimycalins A and B represent the first examples of the natural N-alkylated hydantoins from the sponge Hemimycale arabica, and provide further insight into the chemical diversity as well as the biological activity of this class of compounds.
Lipoxygenase inhibitors flavonoids from Cyperus rotundus aerial parts
Abstract Cyperus rotundus L. (Suada, Sueda, family: Cyperaceae) is vastly spread in several world's subtropical and tropical regions. It had variable traditional uses and bioactivities. A new
Non contiguous-finished genome sequence and description of Clostridium jeddahense sp. nov.
TLDR
The genome of Clostridium jeddahense strain JCDT, an obligate Gram-positive bacillus, was isolated from the fecal flora of an obese 24 year-old Saudian male and described here.
Mangostanaxanthone VIIII, a new xanthone from Garcinia mangostana pericarps, α-amylase inhibitory activity, and molecular docking studies
Abstract A new xanthone: mangostanaxanthone VIIII [1,3,5,6,7-pentahydroxy-2-(3-methylbut-2-enyl)-8-(3-hydroxy-3-methylbut-1-enyl) xanthone] (5) and four known xanthones: mangostanaxanthones I (1) and
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