Adiponectin differentially regulates cytokines in porcine macrophages.
- M. Wulster-Radcliffe, K. Ajuwon, Jiazhen Wang, J. Christian, M. Spurlock
- Biology, MedicineBiochemical and Biophysical Research…
- 9 April 2004
UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis
- K. Ikeda, Qianqian Kang, S. Kajimura
- BiologyNature Network Boston
- 30 September 2017
A noncanonical thermogenic mechanism through which beige fat controls whole-body energy homeostasis via Ca2+ cycling is uncovered through which it functions as a 'glucose sink' and improves glucose tolerance independently of body weight loss.
Board-invited review: the biology and regulation of preadipocytes and adipocytes in meat animals.
- G. Hausman, M. Dodson, W. Bergen
- BiologyJournal of Animal Science
- 1 April 2009
This review is focused on current knowledge about the biology and regulation of the important cells of adipose tissue: preadipocytes and adipocytes.
Basal endogenous losses of amino acids in protein nutrition research for swine and poultry
- O. Adeola, P. Xue, A. Cowieson, K. Ajuwon
- Biology
- 1 November 2016
Palmitate Activates the NF-κB Transcription Factor and Induces IL-6 and TNFα Expression in 3T3-L1 Adipocytes
- K. Ajuwon, M. Spurlock
- Biology
- 1 August 2005
Data indicate that palmitate induces inflammation in adipocytes, and that this is not a generalized effect of all SFA, and suggests that PI3K may act constitutively to suppress inflammation.
Adiponectin inhibits LPS-induced NF-kappaB activation and IL-6 production and increases PPARgamma2 expression in adipocytes.
- K. Ajuwon, M. Spurlock
- Biology, MedicineAmerican Journal of Physiology. Regulatory…
- 2005
Findings indicate that adiponectin may be a local regulator of inflammation in the adipocyte and adipose tissue via its regulation of the NF-kappaB and PPARgamma2 transcription factors.
Palmitate activates the NF-kappaB transcription factor and induces IL-6 and TNFalpha expression in 3T3-L1 adipocytes.
- K. Ajuwon, M. Spurlock
- BiologyJournal of NutriLife
- 2005
Data indicate that palmitate induces inflammation in adipocytes, and that this is not a generalized effect of all SFA, and PI3K may act constitutively to suppress inflammation.
Effect of threonine deficiency on intestinal integrity and immune response to feed withdrawal combined with coccidial vaccine challenge in broiler chicks
- Qian Zhang, X. Chen, S. Eicher, K. Ajuwon, T. Applegate
- Biology, MedicineBritish Journal of Nutrition
- 1 December 2016
Thr deficiency worsened the detrimental effects of combined feed withdrawal and coccidial infection on growth performance and oocyst shedding by impairing intestinal morphology, barrier function, lymphocyte profiles and their cytokine expressions.
Adiponectin inhibits LPS-induced NF-κB activation and IL-6 production and increases PPARγ2 expression in adipocytes
- K. Ajuwon, M. Spurlock
- Medicine, Biology
- 1 May 2005
The objective of this study was to establish a steady-state relationship between adiponectin concentrations and insulin resistance and tumor necrosis factor-α levels.
Adipocytes, myofibers, and cytokine biology: new horizons in the regulation of growth and body composition.
- S. Jacobi, N. Gabler, K. Ajuwon, J. Davis, M. Spurlock
- BiologyJournal of Animal Science
- 1 April 2006
The ability to recognize antigens and produce regulatory molecules strategically positions adipocytes and myofibers to regulate growth locally, and to reciprocally regulate metabolism peripherally, as an interface between energy status and immune function.
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