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Substrate specificity of recombinant osteoclast-specific cathepsin K from rabbits.
- K. Aibe, H. Yazawa, +4 authors K. Honda
- Biology, Medicine
- Biological & pharmaceutical bulletin
- 15 August 1996
The substrate specificity ofCathepsin K, as determined using various chemogenic substrates, showed different characteristics from cathepsins L and S, and benzyloxycarbonyl-Gly-Pro-Arg-7-(4-methyl)coumaryl-amide was the most suitable substrate for catheptic K, but was hardly hydrolyzed by cathepsypsin L. Expand
Oral Administration of Lactobacillus plantarum Strain AYA Enhances IgA Secretion and Provides Survival Protection against Influenza Virus Infection in Mice
- Yosuke Kikuchi, Ayami Kunitoh-Asari, +7 authors S. Hachimura
- Biology, Medicine
- PloS one
- 22 January 2014
A novel immunoregulatory role is revealed of the L. plantarum AYA strain which enhances mucosal IgA production and provides protection against respiratory influenza virus infection. Expand
Roles of CLCA and CFTR in Electrolyte Re-absorption from Rat Saliva
- K. Ishibashi, J. Yamazaki, K. Okamura, Y. Teng, K. Kitamura, K. Abe
- Biology, Medicine
- Journal of dental research
- 1 December 2006
These results represent the first in vivo evidence for a physiological significance of rCLCA, along with CFTR, in transepithelial Cl− transport in the ductal system of the rat submandibular gland. Expand
The Effects of Tyramine on Salivary Flow Rate and Protein Secretion by Rat Submandibular Glands
P-tyramine may activate both the α1- and β1adrenoceptors in the submandibular glands of rats directly or indirectly and be significantly reduced with all autonomic blockers except the lowest doses of β-blockers, atropine, and yohimbine. Expand
Cyclic Mechanical Strain Induces Interleukin-6 Expression via Prostaglandin E2 Production by Cyclooxygenase-2 in MC3T3-E1 Osteoblast-like Cells
Abstract Interleukin (IL)-6, produced by osteoblasts, is one of the key cytokines that promote bone resorption. This study examined the effect of cyclic mechanical strain on the expression of IL-6… Expand
The effects of electrical and pharmacological stimulation on the types of proteins secreted by rat parotid and submandibular glands.
No differences in the types or proportions of the different proteins were detected in saliva elicited by electrical stimulation of the parasympathetic nerve to the glands, by cholinergic or by α- or β-adrenergic agonists, despite large differences in salivary flow rates and protein concentrations in response to those different stimuli. Expand
Dopamine-induced secretion of protein and of some electrolytes by rat submandibular and parotid glands.
Parotid secretion was partially blocked by both phentolamine and haloperidol, suggesting that dopamine is also acting on α-adrenergic and on specific dopamine receptors, and the submandibular gland is able to secrete different types of proteins in response to α-ADrenergic agonists as opposed to β- adrenergic or cholinergic agonist. Expand
The Secretion of Protein and of Some Electrolytes in Response to a- and β- Adrenergic Agonists by Rat Parotid and Submandibular Salivary Glands Enlarged by Chronic Treatment with Isoproterenol
In comparison with control rats, chronic administration of isoproterenol (IPR) caused enlargement of the parotid and submandibular glands and the synthesis of apparently new proteins, probably by… Expand
Secretion of Protein by the Submandibular Glands of the Rat, Mouse, and Hamster in Response to Various Parasympatho- and Sympatho-mimetic Drugs
The types of proteins secreted by the submandibular glands of rats in response to high doses of α-adrenergic agonists are electrophoretically different from those secreted in response in mice and hamsters, but, in rodents, they appear to be independent of the nature of the stimulus. Expand
A new method for the study of the formation and transformation of calcium phosphate precipitates: effects of several chemical agents and Chinese folk medicines.
The method was used to study substances which influence the formation of amorphous calcium phosphate and its transformation to hydroxyapatite, such as albumin, casein, chondroitin sulphate, phospholipid, ATP, Mg2+, Sr2+, pyrophosphate and several Chinese folk medicines. Expand