K. Abe

Publications131
h-index37
Citations5,890
Highly Influential Citations277
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Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
TLDR
The Af293 genome sequence provides an unparalleled resource for the future understanding of this remarkable fungus and revealed temperature-dependent expression of distinct sets of genes, as well as 700 A. fumigatus genes not present or significantly diverged in the closely related sexual species Neosartorya fischeri, many of which may have roles in the pathogenicity phenotype.
Genome sequencing and analysis of Aspergillus oryzae
TLDR
Specific expansion of genes for secretory hydrolytic enzymes, amino acid metabolism and amino acid/sugar uptake transporters supports the idea that A. oryzae is an ideal microorganism for fermentation.
Aspergillus nidulans HOG pathway is activated only by two‐component signalling pathway in response to osmotic stress
TLDR
The differences between the AnHOG and the yeast HOG pathways are discussed, and it is found that besides HogA, PbsB can activate another Hog1p MAPK orthologue, MpkC, in A. nidulans, although mpkC is dispensable in osmoadaptation.
MpkA-Dependent and -Independent Cell Wall Integrity Signaling in Aspergillus nidulans
TLDR
The transcriptional regulation of mpkA and of CWGs via CWIS in A. nidulans differs significantly from that in S. cerevisiae, and MPkA transcription seems to be autoregulated by CWIS via MpkA but not by RlmA or AnSwi4-AnSwi6.
A defect of LigD (human Lig4 homolog) for nonhomologous end joining significantly improves efficiency of gene-targeting in Aspergillus oryzae.
Purification and characterization of a biodegradable plastic-degrading enzyme from Aspergillus oryzae
TLDR
Determination of the affinities for different chemicals indicated that the most preferred substrate for the enzyme would consist of butyric acid and n-hexanol, and the environment of the catalytic pocket, which is divided into carboxylic acid and alcohol recognition sites, was investigated.
The SskA and SrrA Response Regulators Are Implicated in Oxidative Stress Responses of Hyphae and Asexual Spores in the Phosphorelay Signaling Network of Aspergillus nidulans
TLDR
When examined these mutant strains under various conditions stressful for hyphal growth and asexual spore development, two of them showed a marked phenotype of hypersensitivity to oxidative stresses, indicative of the physiological importance of the His-Asp phosphorelay signaling network involving the SskA and SrrA response regulators.
Functional analysis of C2H2 zinc finger transcription factor CrzA involved in calcium signaling in Aspergillus nidulans
TLDR
Comprehensive transcriptional analysis with DNA microarrays indicated that CrzA regulates the expression of a vacuolar Ca2+/H+ exchanger gene in response to external calcium stimuli, suggesting the importance of calcium homeostasis for adaptation to osmotic stress, a universal stress in filamentous fungi.
Dynamics of cell wall components of Magnaporthe grisea during infectious structure development
TLDR
A dynamic change of composition of cell wall polysaccharides occurs during plant infection in M. grisea, which spatially and functionally masks β‐1,3‐glucan and chitin in the cell wall of infectious hyphae.
Novel Hydrophobic Surface Binding Protein, HsbA, Produced by Aspergillus oryzae
TLDR
Results suggest that when HsbA is adsorbed onto the PBSA surface, it recruits CutL 1, and that when CutL1 is accumulated on the PB SA surface,It stimulates PBSA degradation via the CutL2 polyesterase.
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