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Flavonoids as Potent Scavengers of Hydroxyl Radicals.
TLDR
Flavonoids, as natural plant antioxidants and essential component of the human diet, are reviewed as compounds interacting with the production of hydroxyl radicals and the structure of the flavonoids is discussed.
Berberine in Cardiovascular and Metabolic Diseases: From Mechanisms to Therapeutics
TLDR
A timely overview of the pharmacological properties and therapeutic application of BBR in CVMD is provided, and recent pharmacological advances which validate BBR as a promising lead drug against CVMD are underlined.
Anthocyanins in purple and blue wheat grains and in resulting bread: quantity, composition, and thermal stability
TLDR
These kinds of wheat, cultivated in the Czech Republic, are suitable for baking bread, since intake of anthocyanins may play an important role in the prevention of human diseases.
Natural Products to Counteract the Epidemic of Cardiovascular and Metabolic Disorders.
TLDR
The present review aims to serve as an "opening" of this special issue of Molecules, presenting key historical developments, recent advances, and future perspectives outlining the potential of natural products for prevention or therapy of cardiovascular and metabolic disease.
C-geranyl compounds from Paulownia tomentosa fruits.
TLDR
Five geranylflavonoids, one prenylated flavonoid, and a simple flavanone were isolated from an ethanolic extract of Paulownia tomentosa fruit, with diplacone proving to be the best antioxidant, although the most cytotoxic compound.
Evaluation of anti-inflammatory activity of prenylated substances isolated from Morus alba and Morus nigra.
TLDR
The cytotoxicity and their antiphlogistic activity, determined as the attenuation of the secretion of TNF-α and IL-1β and the inhibition of NF-κB nuclear translocation in LPS-stimulated macrophages, were evaluated for compounds 1-10.
Young Barley Indicates Antitumor Effects in Experimental Breast Cancer In Vivo and In Vitro
TLDR
An antitumor effect is proposed for the mixture of phytochemicals present in young barley in a breast cancer model by preventing cell cycle progression and extended incubation with barley.
Prenylated Flavonoids from Morus alba L. Cause Inhibition of G1/S Transition in THP-1 Human Leukemia Cells and Prevent the Lipopolysaccharide-Induced Inflammatory Response
TLDR
From the three compounds tested, cudraflavone B showed the strongest effects on cell cycle progression and viability of tumor and/or immortalized cells and also on inflammatory response of macrophage-like cells, respectively.
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