K. Yano

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The Patlak plot method is widely used in general clinical practice to calculate mean cerebral blood flow (mCBF) because it does not require arterial blood sampling and the procedure used is relatively simple. However, it has been pointed out that the calculation is affected by operator subjectivity and experience, and reproducibility is poor when the(More)
The following process conventionally has been followed to develop quantitative images of cerebral blood flow: (1) mean cerebral blood flow (mCBF) is calculated by the Patlak plot method; (2) a SPECT slice that includes the basal ganglia is selected; and (3) based on the value of mCBF calculated by the Patlak plot method, the SPECT slice is corrected by the(More)
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