K. Vijayanarayana

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Buccal films of ondanstron hydrochloride were fabricated from mucoadhesive polymer, chitosan, and polyvinyl pyrrolidone (PVP K30) for the purpose of prolonging drug release and improving its bioavailability. All fabricated film formulations prepared were smooth and translucent, with good flexibility. The weight and thickness of all the formulations were(More)
BACKGROUND The purpose of this study was to formulate and evaluate nano lipid vesicles of methotrexate (MTX) for its anti-rheumatoid activity. METHODS In this study the principle of both active as well as passive targeting using MTX-loaded stealth liposomes as per the magic gun approach was followed. Stealth liposomes of MTX were prepared by thin-film(More)
WHAT IS KNOWN AND OBJECTIVE Chronic obstructive pulmonary disease (COPD), a preventable and treatable disease, has been described as '10% medication and 90% education'. Extreme physician scarcity limits the implementation of quality healthcare delivery in India. We conducted this study to evaluate the effectiveness of clinical pharmacist intervention on(More)
The rhizomes of Curculigo orchioides Gaertn. (Amaryllidacea) is an important Ayurvedic as well as Unani drug. It is present in several drug formulations used in the treatment of menorrhagia and other gynecological problems. In this study, we conducted a comparative study of estrogenic activity of alcoholic extract of Curculigo orchioides with(More)
Treatment of chronic conditions like diabetic foot ulcer (DFU) is challenging due to increased susceptibility for infection and delayed wound healing. Complexity of existing therapy, adverse effects and microbial resistance emphasizes the need of an alternative approach for the management of DFU. The increasing body of evidence associated with probiotic(More)
Studies have reported that health-related quality of life (HRQoL) is adversely affected by diabetic foot ulcer (DFU). There is a paucity of data on the effects of foot ulcers on HRQoL of diabetes patients in our population. Because South-Asians, especially Indians, have unique features related to diabetes and its complications, generalizing the data about(More)
No: PGI43<lb>Figure 3 Types of patients and outcomes of hospitalized patients receiving TPN<lb>Figure1. Gender wise distribution (%) of inpatients receiving TPN therapy among male<lb>and female Figure 2. Indication for TPN in hospitalized patients in surgery wards<lb>Type of patient<lb>Incidence (%) Alive (%) Death (%)(More)
Efficient approach to the synthesis of a series of triazolothiadiazole analogs of ibuprofen has been carried out using microwave energy. Thus a series of 1,2,4-triazolo[3,4-b]-thiadiazoles 5 were synthesized starting from 4-amino-3-[1-(4-isobutylphenyl)ethyl]-5-mercapto-1,2,4-triazole 3 and different aromatic acids using phosphorous oxychloride as cyclizing(More)
01/01/2009 and 31/01/2013 were identified in The Health Improvement Network (THIN) database. Patients were excluded if they had history of; chronic kidney disease stage 4/5, cancer, neuropathic pain, sciatica/radiculopathy, diabetes, back pain or a prior prescription for a study drug. Patients were classified as responders if they were either “cured”(More)
BACKGROUND The impact of diabetes on health-care expenditures has been increasingly recognized. To formulate an effective health planning and resource allocation, it is important to determine economic burden. OBJECTIVE The objective of this study is to assess the cost of illness (COI) for diabetic inpatients with or without complications. METHODOLOGY(More)
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