K. Venkata Ratnam

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BACKGROUND Little is known of the course and prognosis of hypersensitivity vasculitis (HV). METHODS Sixty-one cases of idiopathic HV were biopsied and followed-up for 5 years. RESULTS There were two predominant patterns of presentation: palpable purpura (PP) and vasculitic ulcers (VU). The former was self-limiting, whereas the prognosis of the latter(More)
  • K V Ratnam
  • 1988
During a 10-year period (1976-1985), eight Chinese patients from a population of 2.5 million fulfilled the criteria for dermatitis herpetiformis and linear IgA bullous dermatosis (LABD). These rare diseases among Asians presented during the third decade of life with homogenous linear IgA deposits along the dermoepidermal junction in four of the eight cases.(More)
Leukemia cutis is an uncommon manifestation of leukemia that is strongly associated with the presence of extramedullary disease at other sites. Patients usually present with leukemia cutis concomitantly with systemic leukemia or after leukemia has been diagnosed. Acute monocytic, myelomonocytic, and the T-cell leukemias show the highest incidence of(More)
BACKGROUND Pemphigus vulgaris is characterized by relapses and remission, and there are currently no sensitive markers to predict remission. OBJECTIVE Our purpose was to determine if direct immunofluorescence (DIF) performed during clinical remission of pemphigus is useful in management of the disease. METHODS Twenty-eight patients with pemphigus that(More)
We studied 100 cases of chronic cutaneous discoid lupus erythematosus (DLE) to evaluate the diagnostic sensitivity of immunoreactant deposition and its possible role in basement membrane thickening. Histopathology was diagnostic in 71% of cases. Sixty-two percent (41/66) of lesions with thickened and 50% (17/34) with normal basement membrane had(More)
A study was conducted on 100 Singapore transsexual prostitutes in an attempt to discover AIDS awareness and any precautions which might have been taken by the prostitutes to limit their exposure to the AIDS virus. The results are as follows: the age, race and educational levels of the transsexuals were recorded. 55% of the transsexuals were Chinese, 36%(More)
Purpura simplex manifests clinically as macular purpuric and petechial pigmented, golden, annular, or lichenoid lesions. These subtypes have been termed Schamberg's purpura, lichen aureus, Majocchi's purpura, and Gougerot-Blum purpura. Histologically, there is inflammation and hemorrhage without fibrinoid necrosis of vessels. One hundred seventy-four cases(More)
Twenty-two newly diagnosed patients with pemphigus were randomly divided into two groups of 11 each. One group was placed on a high-dose prednisolone (120 mg/day) therapy and the other group on a low-dose (60 mg/day) therapy. The patients were followed for 5 years. Although a rapid initial control of the pemphigus appeared to be achieved with the high-dose(More)