K. U. Zerbian

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Patients with International Union Against Cancer (UICC) stage IIb and III colon cancer and stage II and III rectal cancer may receive adjuvant chemotherapy with 5-fluorouracil (5-FU). High levels of thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) have been associated with resistance to 5-FU in advanced colorectal cancer. The aim of this(More)
Histochemical investigations on the ovaries of rats, mice and guinea pigs revealed a variable behaviour of the azolesterases (= cholinesterase and acetylcholinesterase) in granulosa, theca and theca organ. The differentiation of these enzymes was carried out with DFP, iso-OMPA and 284 C 51. The distribution of β-hydroxybutyrate dehydrogenase closely(More)
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