K. Stark

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OBJECTIVE Aminoflavone (AF) acts as a ligand of the aryl hydrocarbon receptor (AhR). Expression of estrogen receptor α (ERα) and AhR-mediated transcriptional induction of CYP1A1 can sensitize breast cancer cells to AF. The objective of this study was to investigate the combined antitumor effect of AF and the histone deacetylase inhibitor vorinostat for(More)
Patients with metastatic triple-negative breast cancer (TNBC) have a poor prognosis. New approaches for the treatment of TNBC are needed to improve patient survival. The concept of synthetic lethality, brought about by inactivating complementary DNA repair pathways, has been proposed as a promising therapeutic option for these tumors. The TNBC tumor type(More)
—Biosurveillance, a relatively young field, has recently increased in importance because of its relevance to national security and global health. Databases and tools describing particular subsets of disease are becoming increasingly common in the field. However, a common method to describe those diseases is lacking. Here, we present the Anthology of(More)
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