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The increase in UV irradiation on earth due to the stratospheric ozone depletion represents a major environmental threat to the skin increasing its risk of photooxidative damage by UV-induced… Continue Reading
This study was undertaken to investigate the requirement of β2-integrins (CD11/CD18) for extravasation of neutrophils in mice. After intraperitoneal thioglycollate injection, an in vivo model of… Continue Reading
Publisher Summary The skin is always in contact with oxygen and is increasingly exposed to ultraviolet (UV) irradiation. Therefore, the risk of photo-oxidative damage of the skin induced by reactive… Continue Reading
Using gene targeting in mouse embryonic stem cells, it is possible to introduce diverse mutations into specific genes. Using these methods, various laboratories have reported mutations for a variety… Continue Reading