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Neurofibromatosis 2 (NF2) is a dominantly inherited disorder characterized by the occurrence of bilateral vestibular schwannomas and other central nervous system tumors including multiple meningiomas. Genetic linkage studies and investigations of both sporadic and familial tumors suggest that NF2 is caused by inactivation of a tumor suppressor gene in(More)
The coupling of data and knowledge has a synergistic effect when building an intelligent data base. The goal i s to integrate the data and knowledge almost to the point of indistinguishability, therefore permitting them to be used interchangeably. Examples given in this paper suggest that Case-Based Reasoning i s a more integrated way to link data and(More)
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