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Oncogenic hyperplasia is the first and inevitable stage of formation of a (solid) tumor. This stage is also the core of many other proliferative diseases. The present work proposes the first minimal model that combines homeorhesis with oncogenic hyperplasia where the latter is regarded as a genotoxically activated homeorhetic dysfunction. This dysfunction… (More)

Many features of living systems prevent the application of fundamental statistical mechanics (FSM) to study such systems. The present work focuses on some of these features. After discussing all the basic approaches of FSM, the work formulates an extension of the kinetic theory paradigm (based on the reduced one-particle distribution function) that exhibits… (More)

A few previous works of the authors derived and discussed the space-time mathematical description, the PhasTraM model, for oncogenic hyperplasia regarded as a genotoxically activated homeorhetic dysfunction. The model is based on the fluid-to-solid-and-back transitions and nonlinear reaction-diffusion equation relevant to a series of the key biomedical… (More)

- Damian Borys, Magdalena Szeremet, Krzysztof Psiuk-Maksymowicz, D Borys, M Szeremet, K Psiuk-Maksymowicz
- 2016

1 Summary. The goal of our work was an initial preprocessing of dermoscopic images towards accurate lesion border detection. Four algorithms were proposed and analyzed: MS – algorithm using mean shift clustering, HE – algorithm using histogram equalization, TTH – algorithm using the top-hat transform, PCA – algorithm using principal component analysis.… (More)

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