K Panduranga Rao

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Composite microspheres have been prepared from bioactive ceramics such as coralline hydroxyapatite [CHA, Ca10(PO4)6(OH)2] granules, a biodegradable polymer, gelatin and an antibiotic, gentamicin. In our earlier work, we have shown a gentamicin release from CHA granules--chitosan composite microspheres. In the present investigation, an attempt was made to(More)
Graft polymerization of glycidylmethacrylate (GMA) onto coralline hydroxyapatite (CHA) was carried out using potassium persulfate (K2S2O8) and sodium metabisulfite (Na2S2O5) as initiators in aqueous medium. To optimize the reaction conditions for getting maximum grafting yield, the concentrations of backbone, monomer, initiator, temperature and time were(More)
Prot A7, a polypeptidic proteinoid composed of seven different amino acids, was synthesized and microspheres of 1-5 microm size were prepared by the self-assembly process. The morphological characterization of the microspheres was carried out using optical microscopy and SEM (scanning electron microscopy). Emphasis also has been made on studying the(More)
In various forms of purified collagen (powder of insoluble collagen from bovine skin, fibers from rat tail tendons, membrane from bovine gut), carboxyl groups were activated by carbodiimide to allow covalent binding of heparin. Collagen powder and collagen fibers from rat tail tendons were also incubated in a heparin solution under the same reaction(More)
The partial conversion of coralline hydroxyapatite (HA) into tricalcium phosphate (TCP) catalyzed by the thermal decomposition of silver oxide was investigated. The thermal analysis of HA powder mixed with 5 mol % Ag2O indicated the decomposition of silver oxide to be around 550 degrees C in the presence of HA. Subsequently a functional gradient structure(More)
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