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e22083 Background: ErbB2 has been known to be important for gallbladder carcinogenesis. Supporting this, the gene amplification of HER2 was found in ca. 20% of human gallbladder carcinoma (GBC) (Kawamoto, et al. Gastrointest Cancer Res 2007). Following these results, a Phase II study of trastuzumab for treatment of GBC (NSC 688097) is being conducted.(More)
A polyhydroxyoalkanoate depolymerase was partially purified from Esherichia coli cells harboring the PHA depolymerase gene (phaZ) of Pseudomonas oleovorans. The partially purified enzyme was characterized. The poly(3-hydroxyoctanoate)-hydrolytic activity of PhaZ was determined by an analysis of the reaction product with gas-liquid chromatography. The full(More)
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