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- Jeffrey Kuethe, Yong-Li Zhong, +7 authors Tao Pei
- Organic letters
- 2013

The development of a practical, asymmetric synthesis of the hepatitis C virus (HCV) protease inhibitor MK-5172 (1), an 18-membered macrocycle, is described.

- T Bergeron, R Zhang, +5 authors V Misra
- Veterinary and comparative oncology
- 2013

The objective of this study was to determine whether the protein Zhangfei could suppress the unfolded protein response (UPR) and growth of osteosarcoma cells. Dog (D-17) and a human (Saos-2) osteosarcoma cells were infected with adenovirus vectors expressing either Zhangfei or the control protein beta- galactosidase. We monitored cell growth as well as… (More)

- H. Hübner, H. Kremer, K. O. Linn, W. Schwering
- Commun. ACM
- 1970

- H. Hübner, H. Kremer, K. O. Linn
- Commun. ACM
- 1970

c o m m e n t This procedure minimizes a function using the method of Broyden [1]. The parameters are described as follows, n is the number of independent variables, iterations is an upper limit on the number of iterations allowed. On exit number is the actual number of iterations taken, maxiters is the maximum number of function evaluations allowed on each… (More)

- H. Hübner, H. Kremer, K. O. Linn, W. Schwering
- Commun. ACM
- 1970

c o m m e n t This procedure minimizes a function using the method of Broyden [1]. The parameters are described as follows, n is the number of independent variables, iterations is an upper limit on the number of iterations allowed. On exit number is the actual number of iterations taken, maxiters is the maximum number of function evaluations allowed on each… (More)

- K O Linn
- Biomedizinische Technik. Biomedical engineering
- 1977

- K O Linn
- Pflügers Archiv : European journal of physiology
- 1972

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