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To investigate the steroidogenic function of human corpora lutea, during the menstrual cycle, slices of seven corpora lutea obtained at various stages in the luteal phase were incubated with [1-14C]acetate; four of them were incubated with [4-14C]pregnenolone simultaneously. Incorporation or conversion of 14C radioactivity into progestins, androgens, and(More)
Slices of each of the six antral follicles at different stages of atresia isolated from ovaries of six patients with or without pretreatment with HCG before laparotomy, were incubated with [1-14C] acetate. Incorporation into progestins, androgens and oestrogens was assessed by the reverse dilution technique with recrystallization to constant specific(More)
Slices of human corpora lutea of menstruation at different stages, or of inner and outer layers consisting of pure granulosa lutein cells and combined theca and granulosa lutein cells respectively, were incubated with [4-14C]-pregnenolone or with [4-14C]-androstenedione respectively. Conversion of 14C-radioactivity to progestins, androgens and/or estrogens(More)
To examine androgenic potential of polycystic ovaries (PCO), slices of follicular and stromal tissues from the same ovary obtained by wedge resection from two markedly, two moderately and one slightly enlarged PCO were incubated separately with [1-14C] acetate. Incorporation into progestins, androgens and estrogens was assessed by reverse dilution technique(More)
  • K Nihnobu
  • Nihon Sanka Fujinka Gakkai zasshi
  • 1985
To investigate the interrelation between steroidogenic function of granulosa and theca lutein cells of the human corpus luteum, twelve corpora lutea of menstruation and pregnancy were divided into inner and outer layers, each of which was histologically confirmed to be composed of pure granulosa lutein cells (GL) or GL plus theca lutein cells (TL),(More)
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