K. N. Ponnuswamy

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To determine whether and how common polymorphisms are associated with natural distributions of iris colors, we surveyed 851 individuals of mainly European descent at 335 SNP loci in 13 pigmentation genes and 419 other SNPs distributed throughout the genome and known or thought to be informative for certain elements of population structure. We identified(More)
The simple mating designs provide unbiased estimates for genetic components of variance (additive genetic variance and dominance variance) under the assumption of no epistatic effect. There is empirical evidence, however, that suggests the existence of epistatic gene effects. The triallel and double cross mating designs permit the estimation of epistatic(More)
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