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A new technique of sedation for children is described, in which midazolam (0.2 mg.kg-1) was administered topically by the nasal route, followed by ketamine (9.0 mg.kg-1) administered rectally in 32 patients breathing air spontaneously. Sedation was good in 23, seven required further ketamine (1.0 mg.kg-1 i.v.), and in two, halothane was introduced. There(More)
Respiratory effects of nitrous oxide and isoflurane were studied in 13 children (mean age 45.6 +/- 19.3 months, mean weight 14.9 +/- 4.8 kg) during surgery under continuous extradural anaesthesia. Three different anaesthetic states were studied: isoflurane 0.5 MAC in oxygen (27 study periods), isoflurane 0.5 MAC with 50% nitrous oxide (32), isoflurane 1 MAC(More)
Changes in ventilatory variables (VE, VE, f, Tl/Ttot, VT/Tl, PE'CO2) were studied in 12 unpremedicated children, weighing between 10 and 20 kg, during halothane anaesthesia. At an inspired concentration of 0.5% halothane, respiratory rate increased, VT decreased, and VE did not change markedly. When the inspired halothane concentration increased further,(More)
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