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A new technique of sedation for children is described, in which midazolam (0.2 mg.kg-1) was administered topically by the nasal route, followed by ketamine (9.0 mg.kg-1) administered rectally in 32 patients breathing air spontaneously. Sedation was good in 23, seven required further ketamine (1.0 mg.kg-1 i.v.), and in two, halothane was introduced. There(More)
Changes in ventilatory variables (VE, VE, f, Tl/Ttot, VT/Tl, PE'CO2) were studied in 12 unpremedicated children, weighing between 10 and 20 kg, during halothane anaesthesia. At an inspired concentration of 0.5% halothane, respiratory rate increased, VT decreased, and VE did not change markedly. When the inspired halothane concentration increased further,(More)
Respiratory effects of nitrous oxide and isoflurane were studied in 13 children (mean age 45.6 +/- 19.3 months, mean weight 14.9 +/- 4.8 kg) during surgery under continuous extradural anaesthesia. Three different anaesthetic states were studied: isoflurane 0.5 MAC in oxygen (27 study periods), isoflurane 0.5 MAC with 50% nitrous oxide (32), isoflurane 1 MAC(More)
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