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Hypothalamic orexin neurons project to numerous brain areas, including the ventral tegmental area (VTA), which is involved in motivation and food-seeking behavior. Here we address how exogenously administered orexin-A and endogenous orexin 1 receptor (OX1R) activation in the VTA affects feeding behavior. We hypothesized that orexin-A and OX1R antagonist(More)
Despite intensive efforts over the last 30 years, the mode of insecticide action remains largely undetermined. Cholinergic enzyme systems have been identified as targets of organophosphates (HAYES, 1975) whereas respiratory, cardiovascular, reproductive, and most prominently, neurological dysfunctions are implicated vectors in organochlorine toxicity(More)
Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) receptor agonist, is used as a treatment for Type 2 diabetes mellitus and obesity because it improves glycemia and decreases food intake. Here, we tested whether chronic activation of the GLP-1 receptor system with liraglutide would induce decreases in intake accompanied by changes in proportional food or(More)
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