K. Lakshmi

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OBJECTIVES The purpose of the present study was to investigate the anti-inflammatory properties of aqueous extract of the leaves of H. integrifolia, Planch. MATERIALS AND METHODS The hind paw edema was produced in rats by subplanter injection of carageenan. The aqueous extract of H. integrifolia, Planch. (AHI) at dose (250 and 500 mg/kg p.o) was given to(More)
Two chemometric methods were developed for the simultaneous determination of telmisartan and hydrochlorothiazide. The chemometric methods applied were principal component regression (PCR) and partial least square (PLS-1). These approaches were successfully applied to quantify the two drugs in the mixture using the information included in the UV absorption(More)
Frequent sub graph mining is another active research topic in data mining. A graph is a general model to represent data and has been used in many domains like chemo informatics and bioinformatics. Mining patterns from graph databases is challenging since graph related operations, such as sub graph testing, generally have higher time complexity than the(More)
In this paper, a new meta-heuristic algorithm is proposed for solving combinatorial optimization problems. The proposed algorithm follows the adaptive swarm intelligence technique proposed earlier, but uses the novel concept of multiple swarms. Unlike the existing multi swarm techniques, the swarms in the proposed algorithm are dynamic and operate with a(More)