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BACKGROUND The Dog erythrocyte antigen (DEA) 1 blood group system was thought to contain types DEA 1.1 and 1.2 (and possibly 1.3 [A3]). However, DEA 1.2+ dogs are very rare and newer typing methods reveal varying degrees of DEA 1 positivity. OBJECTIVES To assess if variation in DEA 1 positivity is because of quantitative differences in surface antigen(More)
Human papillomavirus type 16 (HPV16) infects cervical epithelium and is associated with the majority of cervical cancers. The E1E4 protein of HPV16 but not those of HPV1 or HPV6 was found to associate with a novel member of the DEAD box protein family of RNA helicases through sequences in its C terminus. This protein, termed E4-DBP (E4-DEAD box protein),(More)
BACKGROUND Cystinuria is an inherited metabolic disease that is relatively common in dogs, but rare in cats and is characterized by defective amino acid reabsorption, leading to cystine urolithiasis. OBJECTIVES The aim of this study was to report on a mutation in a cystinuric cat. ANIMALS A male domestic shorthair (DSH) cat with cystine calculi, 11(More)
BACKGROUND Based upon serology, >10 canine blood group systems have been reported. OBJECTIVE We surveyed dogs for dog erythrocyte antigen (DEA) 1 and 2 new blood types (Kai 1 and Kai 2), and some samples also were screened for Dal and DEA 3, 4, and 7. METHODS Blood samples provided by owners, breeders, animal blood banks, and clinical laboratories were(More)
BACKGROUND Difficulties with the direct antiglobulin test (DAT) and its apparent lack of sensitivity and specificity for immune-mediated hemolytic anemia (IMHA) in dogs have raised skepticism regarding its diagnostic value. OBJECTIVE To compare different DATs and other hematologic parameters in dogs. ANIMALS Anticoagulated blood samples from 59(More)
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