K Iu Reznikov

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The cell cycle kinetics of individual clones of cells in the embryonic cortex were studied to determine the amount of heterogeneity among cortical progenitors. This kinetic heterogeneity may be the first sign of heterogeneous differentiation in the proliferating cortical germinal zone. Retroviral lineage tracing of clonal progeny in the embryonic day 16(More)
Cell cycle parameters were estimated using the cumulative 3H-thymidine S-phase labeling and percentage of labeled mitoses methods in the embryonic day 14 and 15 germinal zone of the rat cerebral cortex. The shortest cell cycle time was seen in the dorsal neocortex and the longest in the lateral neocortex and fimbria (the latter also had a low growth(More)
The local cellular proliferation takes place in the inner part of the dentate gyrus granular layer, the subgranular zone, of mice. The proliferating cells of the subgranular zone are one of two sources of postnatal neurogenesis of the granular layer (another source-cells of the subependymal zone). The subgranular zone becomes markedly thinner with the age(More)
The mitotic and pyknotic indices were counted in the local germinative zones of Ammon's horn and dentate gyrus of normal mice from embryonic day 18 (ED 18) to postnatal day 60 (PD 60). The local germinative zone of Ammon's horn (the suprafimbrial zone) forms from ED 16 but the first pyknoses appear in it from ED 20. After a rapid increase of the mitotic and(More)
Mapping on arrangement of mitoses (M) and pyknoses (P) has been performed in the mouse developing hippocamp. Analysis on the M arrangement confirms the data known on the hippocampal germinative zones and time of their reduction in the mouse ontogenesis. Previously unknown germinative zone of Ammon's horn has been revealed--the suprafimbrial zone that exists(More)
By means of computer analysis, size distribution of neurons and glial cells together with the label of 3H-thymidin labelled cells were studied in cytoarchitectonic layers of the field 1 in the mouse parietal cortex injected with the isotope on the 5th day of life and killed 1 month later. In some animals, 3 days before 3H-thymidin injection, the parietal(More)
After the injury of the thalamus right hemisphere in tadpoles and young frogs X. laevis, 3H-thymidine incorporated in the cells of the thalamus ventricular zone, but not in the middle and large neurons of the type of neurons of the trigeminal nerve mesencephalic nucleus and the large ganglion cells of VI and VIII layers of the thalamus cortex. The brain(More)