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Use of monoclonal antibodies (Mc 3 and Mc 8) prepared against human mammary-epithelial antigens of human mild fat globule membranes has enabled characterization of breast carcinoma (BC) associated antigens (BCAA), antibodies, and circulating immune complexes (CIC). For this study, BC patients were grouped on the basis of measurable tumor burden: Group I(More)
A silicon-on-insulator (SOI) micro-electromechanical system (MEMS) accelerometer, complementary Metal oxide semiconductor (CMOS) readout circuit and simultaneous hermetic encapsulation using low temperature Cu-Cu bonding are investigated for 3D heterogeneous integration of MEMS and CMOS. The MEMS accelerometer is fabricated using bulk micromachining(More)
Recent technical improvements in circulating immune complexes (CIC) detection have resulted in a proliferation of data reporting increased CIC levels in a variety of human diseases. The overall result being a better understanding of the inferred pathogenic role of IC in disease, and their possible clinical significance. We will pay particular attention to(More)
We have investigated the membrane-binding properties of fetal liver cells (FLC) and developed an assay to quantitate circulating immune complexes (CIC) based on complement (C) receptor binding on FLC. Both binding and blocking studies identified FLC membrane receptors for IgG-Fc, C, and antifetal antibodies (FL-Ab), but not IgG F(ab)′2. Fc binding of IgG or(More)
The dynamic relationships of circulating immune complexes (CIC) and associated immune reactants to stage of disease and prognosis in cancer patients have been evaluated for malignant melanoma. Patients were divided into group I patients, with no evidence of disease at sample time; group II patients, with minimal tumor burden; and group III patients, with(More)
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