K H Wangenheim

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For the measurement of long-term residual radiation effect in the murine hematopoietic system a test system was developed that quantifies the proliferation ability of progeny of spleen repopulating cells by the proliferation factor (PF). The PF expresses the ratios of 125IUdR incorporation in the recipient spleens at days 3 and 5 following cell transfusion,(More)
Various agents have been shown to induce differentiation in neoplastic cells. The present study aimed at investigating comparable phenomena induced by high doses of gamma-irradiation in the presence of physiological factors. The erythroleukemic K562 cells were gamma-irradiated or treated with cytosine-arabinoside (Ara-C), and examined for cell size, protein(More)
The proliferation rate of murine hematopoietic cells in regenerating spleen was assayed by a novel technique that analyzes the integrity of stem cells irrespective of their number. It relies on the increment of incorporation of 5-(125I) iodo-2'-deoxyuridine (125IUdR) at day 3 and 5 after transfusion of syngeneic marrow cells in fatally irradiated(More)
Cytological investigations with diploid and autotetraploid plant materials reveal that cytoplasmic growth, including the propagation of autoreduplicating cytoplasmic units such as mitochondria and proplastids, continues during the radiation-induced mitotic delay, thus increasing the ratio of cytoplasmic amount: nuclear ploidy. In accordance with a control(More)
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