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Constant continuous positive airway pressure (CPAP) is the treatment of choice for the obstructive sleep apnea syndrome (OSAS). To enable the pressure to be matched more accurately to actual requirements, and thus increase patient acceptance, an autoadjusting device based on the measurement of upper airway impedance was developed (APAP(FOT)). We(More)
Abnormalities in the proportions of immunoregulatory T-lymphocytes in bronchoalveolar lavage fluid have been reported in interstitial pulmonary diseases, yet the effect of cigarette smoking on T-cell subsets in bronchoalveolar lavage fluid from normal subjects has not been investigated. We applied an immunoperoxidase technique performed on glass slides(More)
BACKGROUND The forced oscillation technique (FOT) allows analysis of the upper airway impedance and, hence, detection of obstructive sleep apnea. OBJECTIVE To evaluate FOT with respect to sensitivity and to specificity in online detection of sleep-disordered breathing patterns and to compare algorithmic onset detection time with manual onset time markers(More)
The aim of the present study was to determine new reference values and predictive variables for dynamic and static pulmonary compliance in men. The investigation was conducted as a prospective study in healthy, non-smoking men with normal pulmonary function parameters including spirometry, bodyplethysmography and CO diffusing capacity. The esophageal(More)
This document replaces the DGP recommendations published in 1998. Based on recent studies and a consensus conference, the indications, choice and performance of the adequate exercise testing method in its necessary technical and staffing setting are discussed. Detailed recommendations are provided: for arterial blood gas analysis and right heart(More)
Cold passover and heated humidifiers are employed for the prevention of side-effects associated with continuous positive airway pressure (CPAP) treatment. However, to date, it has not been possible to separately measure the humidity of inspired and expired air. The aim of this study was to compare the relative humidity of the inspired air and the water loss(More)
BACKGROUND Measurement of impedance using forced oscillation technique is a sensitive means of detecting airway obstructions, including the obstructive sleep apnea syndrome (OSAS). OBJECTIVE The present study was conducted to determine whether treatment with an automated impedance-controlled continuous positive airway pressure (CPAP) device (APAP(FOT)) is(More)
The most common side effects of nocturnal CPAP treatment are problems affecting the mouth, nose and throat in patients with obstructive sleep apnea syndrome (OSAS). Employing a visual analogue scale, the extent of these complaints in OSAS patients who were investigated for the first time in a sleep laboratory was determined prior to and following the(More)
Evaluating lung volumes, the measured values are compared with predicted values. Determination with nomograms is time consuming and perhaps incorrect. For calculation in a desk-computer, equations with 1 or more variables are necessary. We determined therefore from the single values of the study of Amrein and Herzog, dependent on sex, age and height,(More)