K. H. Künzel

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The posterior cruciate ligament (PCL) can be anatomically divided into three bundles: anterolateral, posteromedial, and posterior oblique. The changes in distance between the femoral and tibial attachment sites of these three bundles were measured in 10 human knee specimens with intact ligamental structures. The femoral to tibial distance (and thus the(More)
GABAARs and GlyRs are considered attractive drug targets for therapeutic intervention and are also increasingly recognized in the context of in vitro neurotoxicity (NT) and developmental neurotoxicity (DNT) testing. However, systematic human-specific GABAAR and GlyR-targeted drug screening and toxicity testing is hampered due to lack of appropriate in vitro(More)
Microglia activation is a neuroinflammatory response to parenchymal damage with release of intracellular metabolites, e.g., purines, and signaling molecules from damaged cells. Extracellular purines can elicit Ca(2+)-mediated microglia activation involving P2X/P2Y receptors with metabotropic (P2Y) and ionotropic (P2X) cell signaling in target cells. Such(More)
We present the current state-of-the art of computer-assisted interstitial (fractionated) brachytherapy as a "picture-book" without wanting to give an in-depth presentation of either hrachytherapy itself or of otolaryngolngic aspects of oncologic treatment. However, our results show that 3Docomputer-assisted navigation techniques can successfully be applied(More)
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