• Citations Per Year
Learn More
Besides the established T-cell property of producing gamma interferon (IFN-gamma), murine T cells additionally possess the ability to produce IFN-alpha and IFN-beta when appropriate inducers such as 10-carboxymethyl-9-acridanone (CMA) or Newcastle disease virus (NDV) are used. Interleukin 2 (IL-2)-dependent murine T-cell lines, but not purified resting(More)
Indomethacin was tested for its ability to augment the cytotoxic capacity of cultured bone marrow-derived macrophages (M phi) against P815 and YAC-1 tumor cells. M phi were obtained from the bone marrow of C57BL/6 mice precultured for 10-14 days and were virtually 100 percent pure. By addition of indomethacin these cells were activated to kill tumor cells(More)
Non-steroidal anti-inflammatory drugs such as carprofen or indomethacin enhanced interferon (IFN) production induced by suboptimal concentrations of 10-carboxymethyl-9-acridanone (CMA) in murine cell cultures. This effect was observed in fibroblasts and in different populations of leukocytes as in peritoneal exudate and spleen cells, and was most pronounced(More)
  • 1